大学化学 >> 2024, Vol. 39 >> Issue (2): 340-346.doi: 10.3866/PKU.DXHX202308067

化学实验 上一篇    下一篇

乙二胺四乙酸铁钠补铁剂制备实验改进

王秀云1, 程嘉硕1, 王一鸣1, 吴浩宇2, 宿艳1, 高瑀茁1, 刘潇彧1, 赵铭宇1, 王春燕1, 崔淼1, 姜文凤1,*()   

  1. 1 大连理工大学化学学院, 辽宁 大连 116024
    2 大连理工大学机械工程学院, 辽宁 大连 116024
  • 收稿日期:2023-08-17 录用日期:2023-09-07 发布日期:2023-09-22
  • 通讯作者: 姜文凤 E-mail:jangwf@dlut.edu.cn
  • 基金资助:
    教育部产学合作协同育人项目(220504807051041);教育部产学合作协同育人项目(202101033007);国家质量工程项目(ZL2021142);国家质量工程项目(ZL2020143);国家质量工程项目(ZL2021301)

Improvement of Sodium Ferric Ethylenediaminetetraacetate (NaFeEDTA) Iron Supplement Preparation Experiment

Xiuyun Wang1, Jiashuo Cheng1, Yiming Wang1, Haoyu Wu2, Yan Su1, Yuzhuo Gao1, Xiaoyu Liu1, Mingyu Zhao1, Chunyan Wang1, Miao Cui1, Wenfeng Jiang1,*()   

  1. 1 School of Chemistry, Dalian University of Technology, Dalian 116024, Liaoning Province, China
    2 School of Mechanical Engineering, Dalian University of Technology, Dalian 116024, Liaoning Province, China
  • Received:2023-08-17 Accepted:2023-09-07 Published:2023-09-22
  • Contact: Wenfeng Jiang E-mail:jangwf@dlut.edu.cn

RichHTML

23

PDF

806

赞

摘要：

本项目将乙二胺四乙酸铁钠(NaFeEDTA)补铁剂制备实验项目进行了改进，将理论知识与实际生产紧密衔接，依据药物制备工艺流程，设置集方案设计、药物制备、结构鉴定、纯度分析等模块于一体的全链条实验内容，将实验项目由验证性实验转变为综合性、设计性实验，引导学生结合制药工艺流程中所涉及到的质量控制、安全生产、环境保护等因素设计实验方案。本实验项目可结合多条专利路线，能激发学生探究兴趣，促进学生自主探究，培养学生方案设计和创新思辨能力，提升学生解决实际问题能力和科学素养，增强专业自信。

关键词: 乙二胺四乙酸铁钠补铁剂制备, 实验改进, 方案设计

Abstract:

This project introduces an enhanced approach to the experimental preparation of Sodium Ferric Ethylenediaminetetraacetate (NaFeEDTA) as an iron supplement. Bridging theoretical concepts with practical manufacturing, the experimental design is aligned with pharmaceutical production processes. It incorporates a comprehensive set of modules, ranging from experimental design and drug preparation to structural identification and purity analysis. The project transforms the experiment from a validation-based exercise to a holistic, design-oriented experiment. Students are guided to consider quality control, safety protocols, and environmental protection as part of their experimental design. This experimental framework accommodates multiple patent pathways, stimulating students' investigative interests and fostering skills in experimental design and critical thinking. It aims to enhance students' problem-solving capabilities, improve their scientific literacy, and boost their confidence in the field.

Key words: Preparation of NaFeEDTA iron supplement, Experiment improvement, Scheme design