大学化学 >> 2026, Vol. 41 >> Issue (9): 264-269.doi: 10.12461/PKU.DXHX202509006

科普 上一篇    下一篇

黑色素瘤暗滋生 疫苗利刃破坚盾

马戈, 沈珍, 陈建成   

  1. 南京大学化学化工学院, 江苏 南京 210023
  • 收稿日期:2025-09-01 录用日期:2025-10-09 发布日期:2026-09-01
  • 通讯作者: 陈建成 E-mail:kschan@nju.edu.cn Kin Shing Chan
  • 基金资助:
    南京大学短期国外专家项目

Melanoma lurks in darkness while vaccine emerges as a potent shield

Ge Ma, Zhen Shen, Kin Shing Chan   

  1. School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, Jiangsu Province, China
  • Received:2025-09-01 Accepted:2025-10-09 Published:2026-09-01
  • Contact: Kin Shing Chan E-mail:kschan@nju.edu.cn

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摘要： 黑色素瘤是一项困扰人类许久的疾病，而随着化学、生命科学等的发展，人们已经研发出了许多黑色素瘤的治疗方法，本文主要介绍黑色素瘤的形成机制，以及相关的疫苗和免疫检查点抑制剂的疗法。

关键词: 黑色素瘤, 癌症疫苗, 免疫检查点抑制剂, UVB, 多肽合成

Abstract: Melanoma has long posed significant challenges to human health. With advancements in chemistry and life sciences, numerous therapeutic approaches for melanoma have been developed. This article primarily discusses the pathogenesis of melanoma, along with relevant vaccine-based therapies and immune checkpoint inhibitors.

Key words: Melanoma, Cancer vaccines, Immune checkpoint inhibitors, UVB, Peptide synthesis