大学化学 >> 2024, Vol. 39 >> Issue (11): 259-268.doi: 10.12461/PKU.DXHX202402056

化学实验 上一篇    下一篇

对羟基苯乙酮萃取实验研究

蒋历辉1, 董万荣2, 阳华1, 夏涌清2, 彭红建1, 袁俊1, 胡晓倩1, 曾子涵1, 邹应萍1, 罗一鸣1   

  1. 1 中南大学化学化工学院, 长沙 410083;
    2 湖南大学化学化工学院, 长沙 410082
  • 收稿日期:2024-02-26 录用日期:2024-05-21 发布日期:2024-11-09
  • 通讯作者: 蒋历辉, 邹应萍 E-mail:jianglh@csu.edu.cn;yingpingzou@csu.edu.cn
  • 基金资助:
    中南大学课程思政教学改革研究资助项目(2022KCSZ037)；湖南省普通高等学校教学改革研究项目(2023jy133)

Study on Extraction of p-Hydroxyacetophenone

Lihui Jiang1, Wanrong Dong2, Hua Yang1, Yongqing Xia2, Hongjian Peng1, Jun Yuan1, Xiaoqian Hu1, Zihan Zeng1, Yingping Zou1, Yiming Luo1   

  1. 1 College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China;
    2 College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China
  • Received:2024-02-26 Accepted:2024-05-21 Published:2024-11-09
  • Contact: Lihui Jiang, Yingping Zou E-mail:jianglh@csu.edu.cn;yingpingzou@csu.edu.cn

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摘要： 部分高校开设的有机化学萃取实验，采用是乙酸乙酯萃取质量分数为5%的苯酚水溶液，鉴于苯酚具有中等毒性和腐蚀性，在实验操作过程中，如萃取、有机相干燥、蒸馏溶剂回收等实验环节都会挥发，为了绿色化实验，减少指导教师和学生在实验过程中吸入有毒化合物及苯酚对环境的危害，选择了化妆品中常用添加剂对羟基苯乙酮替代苯酚作为研究对象，配制饱和水溶液，分别以乙酸乙酯和二氯甲烷为有机溶剂萃取对羟基苯乙酮，并锻炼学生萃取过程中如何破乳以及对比两种不同溶剂的萃取效果。

关键词: 对羟基苯乙酮, 萃取, 有机化学实验

Abstract: For the organic chemistry extraction experiments in some universities, the aqueous phenol solution (5 wt%) is normally extracted by ethyl acetate. However, phenol has moderate toxicity and corrosiveness, and it volatilizes easily during experimental operations such as extraction, organic phase drying and distillation solvent recovery. To promote greener laboratory practices and reduce the exposure to toxic compounds for both students and experimental mentors, as well as the environmental impact of phenol, the p-hydroxyacetophenone is selected to replace phenol for the lab course in the present work. The p-hydroxyacetophenone is a natural compound, which is widely used as additive in skincare cosmetics. The saturated aqueous solution of p-hydroxyacetophenone is prepared and extracted by the ethyl acetate or dichloromethane. The process of demulsify during the extraction process has been introduced and showed. Furthermore, the extraction efficiencies of these two solvents are compared.

Key words: p-Hydroxyacetophenone, Extraction, Organic chemistry experiments