Microneedle patches have realized the long-sought dream of painless injections while significantly improving transdermal drug delivery efficiency. These innovative devices demonstrate remarkable potential across diverse fields, particularly in cosmetic skincare and therapeutic applications. This article elucidates the scientific principles underlying this “miniature marvel” that alleviates needle phobia, detailing the material composition and manufacturing processes of polymeric microneedles along with their expanding applications in beauty and healthcare. As microneedle technology continues to advance, it is emerging as a transformative innovation in both medical and cosmetic domains, destined to become an integral part of modern healthcare practices.

Molecularly imprinted polymers (MIPs), renowned for their specific recognition capabilities and high selectivity, have emerged as promising candidates for drug delivery systems (DDS). MIPs-based DDS enables targeted and controlled drug release, effectively minimizing side effects while significantly enhancing therapeutic outcomes. This article presents the fundamental concepts of MIPs using vivid, anthropomorphic language, followed by an in-depth exploration of their applications in targeted drug delivery and their potential in the pharmaceutical and healthcare sectors.

Polysiloxanes, among the most versatile organosilicon polymers, feature a backbone composed of repeating Si―O bonds with organic groups attached to the silicon atoms. This unique inorganic-organic hybrid structure imparts exceptional physicochemical stability, physiological inertness, outstanding biocompatibility, remarkable weather and aging resistance, as well as excellent processability to polysiloxane materials. These superior properties have enabled their widespread applications in life sciences and healthcare, including human organ repair/replacement, cosmetic surgery, tissue engineering, medical devices, and drug delivery systems. This review systematically examines the structure-property relationships of polysiloxanes and provides a comprehensive discussion of their applications in biomedical and healthcare fields.

Guided by the educational objective of cultivating high-quality applied talents, this paper proposes a comprehensive experimental module that integrates fundamental knowledge and experimental skills from polymer chemistry, biomedical engineering, and instrumental analysis. In this experiment, calcium phosphate is employed as the calcium source for gelation. By precisely controlling the mixing ratio and process of calcium chloride and sodium phosphate solutions, calcium phosphate particles are uniformly dispersed in sodium alginate, a natural polymer. Under stirring, these particles gradually release calcium ions, which react with sodium alginate to form calcium alginate gel particles with micrometer-scale sizes, while achieving efficient drug encapsulation. Dynamic light scattering technique is employed to evaluate particle size and distribution, and fluorescence spectrophotometry is applied to analyze drug encapsulation efficiency and release behavior. This experimental design is based on current research hotspots and utilizes environmentally friendly materials and methods, ensuring its ecological friendliness. Moreover, the experimental model has potential expandability and can be applied to studies of other responsive polymers and drug carriers. The experiment is designed to simultaneously enhance students’ basic experimental skills and advanced research competence, fostering innovative thinking and independent research abilities. Through guidance in an exploratory learning environment, the module aims to nurture innovative talents capable of driving future scientific development

Compared to traditional drugs, monoclonal antibody (mAb) drugs distinguish themselves through their excellent specificity. They are capable of precisely recognizing and binding to target antigens, accurately localizing to diseased sites, and intervening in specific disease processes, thereby minimizing damage to other parts of the body and reducing side effects. MAb drugs play an important role in disease prevention and treatment, characterized by their unique structural functions, stringent preparation processes, and widely acknowledged safety. This article introduces the structure and functions of mAb drugs, along with their preparation processes, and emphasizes their significant contributions to the treatment of tumor, autoimmune diseases, and infectious diseases.