大学化学 >> 2020, Vol. 35 >> Issue (11): 115-120.doi: 10.3866/PKU.DXHX202006033

所属专题： 化学科普(2020)

科普 上一篇    下一篇

尼古丁的“口供”

吴雨菡1, 郭今心2,*()   

  1. 1 山东大学基础医学院, 济南 250012
    2 山东大学化学化工学院, 济南 250100
  • 收稿日期:2020-06-08 录用日期:2020-07-20 发布日期:2020-08-12
  • 通讯作者: 郭今心 E-mail:jinxinguo@sdu.edu.cn
  • 作者简介:郭今心, Email: jinxinguo@sdu.edu.cn
  • 基金资助:
    2018山东省教育厅新时代医用化学系列课程教学模式改革与创新实践(M2018B350)

"Confession" from Nicotine

Yuhan Wu1, Jinxin Guo2,*()   

  1. 1 School of Basic Medical Sciences, Shandong University, Jinan 250012, P. R. China
    2 College of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P. R. China
  • Received:2020-06-08 Accepted:2020-07-20 Published:2020-08-12
  • Contact: Jinxin Guo E-mail:jinxinguo@sdu.edu.cn

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摘要：

以口供的形式介绍了尼古丁的分子结构和部分生理功能，通过真实案件揭示尼古丁对人体的毒性。结合医学知识，阐述了尼古丁中毒的过程、吸烟上瘾的机理和尼古丁对人体的损害，并对人类健康生活提出禁烟建议。

关键词: 尼古丁, 烟碱型乙酰胆碱受体(nAChRs), 吸烟, 急性尼古丁中毒, 成瘾

Abstract:

This is a piece of confession made by Nicotine where its molecular structure and some physiological functions are introduced. The toxicity of Nicotine on human body has been revealed, based on an authentic suicide case. Combined with medical knowledge, the process of Nicotine intoxication, the mechanism of smoking addition and Nicotine's negative effect on human body, have been presented. Ultimately non-smoking advice is suggested for the sake of human health.

Key words: Nicotine, Nicotinic acetylcholine receptors (nAChRs), Smoking, Acute Nicotine intoxication, Addition