大学化学 >> 2025, Vol. 40 >> Issue (1): 174-184.doi: 10.12461/PKU.DXHX202404147

所属专题: 高水平创新型药学人才培养与化学课程教学

教学研究与改革 上一篇    下一篇

“科教协同”结合“多学科交叉”体系培养复合型药物化学研究生

张岚1, 李郅佳1, 袁子月1, 刘博2   

  1. 1 西南交通大学生命科学与工程学院, 成都 610031;
    2 四川大学生物治疗全国重点实验室, 成都 610041
  • 收稿日期:2024-04-25 录用日期:2024-08-14 发布日期:2025-01-06
  • 通讯作者: 刘博 E-mail:liubo2400@163.com
  • 基金资助:
    国家自然科学基金(22277102,82373193,82172649)

Cultivating Comprehensive Medicinal Chemistry Postgraduates Combined with Science-Education Synergy and Multidisciplinary Interdisciplinary Philosophy

Lan Zhang1, Zhijia Li1, Ziyue Yuan1, Bo Liu2   

  1. 1 School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China;
    2 State Key Laboratory of Biotherapy and Cancer Center, Sichuan University, Chengdu 610041, China
  • Received:2024-04-25 Accepted:2024-08-14 Published:2025-01-06
  • Contact: Bo Liu E-mail:liubo2400@163.com

摘要: 药物化学是药学领域中重要的带头学科,相关人才培养涉及到药物研发过程中的新药创制、药物合成、药物构效、药物体内代谢变化等重要环节。考虑到药物化学学科跨度大、知识覆盖面广,我们从“科教协同”与“多学科交叉”的角度出发,通过比较综合类院校、理工类院校和药学特色院校之间不同的培养优势,从导师制度、培养方案设计、课堂教学方面探索复合型药物化学研究生的培养策略和具体举措。

关键词: 药物化学, 研究生, 培养模式, 科教协同, 多学科交叉

Abstract: Medicinal chemistry is an important leading discipline in the field of pharmacy, with talent cultivation encompassing critical stages in drug discovery, including new drug creation, drug synthesis, structure-activity relationships, and drug metabolism changes in vivo. Given the broad scope and interdisciplinary nature of medicinal chemistry, we compare the different training advantages among comprehensive universities, polytechnic universities and pharmacological institutions from the perspective of “science-education synergy” and “multidisciplinary intersection”. We also explore the training strategies and specific measures for cultivating well-rounded medicinal chemistry postgraduates, focusing on mentorship system, training program design and classroom teaching methods.

Key words: Medicinal chemistry, Postgraduate student, Training model, Science-education synergy, Multidisciplinary intersection