Abstract: Cancer remains a prevalent and challenging disease in modern society. With recent advancements in bionanotechnology, researchers have developed intelligent micro/nanomaterials known as liquid-metal-based robots. This emerging interdisciplinary technology combines biotechnology, materials science, nanoengineering, and mechanical systems. These miniature robots can undergo controlled morphological transformations under external fields, enabling targeted cancer therapy, though the technology remains relatively unknown. Drawing inspiration from the literary classic “Journey to the West”, this study employs anthropomorphic narrative techniques to elucidate the fabrication methods, deformation characteristics, and therapeutic processes of liquid-metal robots in vivo. This article aims to enhance public understanding of the scientific principles underlying these transformative biomedical agents, thereby facilitating their practical clinical applications.

Key words: Liquid metal, Micro/nanorobots, Tumor therapy, Deformation mechanism, Actuation methods