University Chemistry ›› 2022, Vol. 37 ›› Issue (12): 2209051.doi: 10.3866/PKU.DXHX202209051

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Amazing Chiral Spiro Catalyst: Analysis of Problem 8 of the 54th International Chemistry Olympiad

Pingping Tang()   

  • Received:2022-09-20 Accepted:2022-10-08 Published:2022-10-25
  • Contact: Pingping Tang


Chiral compounds are very important in people's life and health. Taking the chiral spiro catalyst developed by the team of academician Zhou Qilin of Nankai University as the main content of the 54th International Chemistry Olympiad, problem 8 investigated the synthesis route of chiral spiro ligand SpiroPAP, the preparation of chiral spiro catalyst Ir-SpiroPAP, and the application of chiral spiro catalyst in the synthesis of natural products.

Key words: Chirality, Spiro catalysts, Organic synthesis, Iridium, Complex