Abstract: The Aldol reaction is a key and challenging topic in the foundational organic chemistry course. In our teaching practice, we have found that explaining the principles of the Aldol reaction based on its reversibility and providing mechanism problems can effectively deepen students’ understanding and awareness of the Aldol reaction, thus enhancing the teaching effectiveness. In this article, we share three typical examples of rearrangement reactions based on reversible Aldol reactions, which can serve as references for teachers and students in their teaching and learning endeavors.

Key words: Aldol reaction, Reversibility, Rearrangement