University Chemistry ›› 2025, Vol. 40 ›› Issue (5): 318-327.doi: 10.12461/PKU.DXHX202407033

• Survey of Chemistry • Previous Articles     Next Articles

Advances in the Application and Preparation of Rhodanine and Its Derivatives

Siran Wang, Yinuo Wang, Yilong Zhao, Dazhen Xu   

  1. National Engineering Research Center of Pesticide, College of Chemistry, Nankai University, Tianjin 300071, China
  • Received:2024-07-04 Revised:2024-10-23 Published:2025-05-21
  • Contact: Dazhen Xu E-mail:xudazhen@nankai.edu.cn

Abstract: Rhodanine and its derivatives are privileged scaffolds commonly found in synthetic compounds. Molecules containing this structural motif often display remarkable biological and pharmacological activities, including antidiabetic, antibacterial, anticancer, and anti-HIV effects. Additionally, they serve as optoelectronic materials, dyes, and analytical reagents. This article provides an overview of the properties and applications of rhodanine and its derivatives, summarizes recent advancements in their preparation methods, and discusses future prospects for research in this field.

Key words: Heterocycle, Biological activity, Carbon disulfide, Alkylamine, Thiazolidinone