Abstract: Pre-laboratory preparation is a crucial component in experimental instruction. The scientific design and effective implementation of preparation not only directly impact the students’ learning effectiveness and the teachers’ instructional efficacy, but also play a pivotal role in cultivating students’ cognitive ability and inquiry spirit, acting as a small lever that can yield significant educational benefits. This paper presents the exploration and summary of an approach adopted by the General Chemistry Experimental Course Team at Wuhan University, which utilizes a blend of online and offline resources to assist lower-year students in their laboratory preparation. It highlights the innovative use of interactive lecture notes and a “Six-Step” preparatory teaching model, aimed at subtly fostering students’ critical thinking and self-learning abilities for steady enhancement.

Key words: General chemistry experiment, Pre-laboratory preparation, Online and offline integration, Interactive lecture notes