Abstract: Honghe University focuses on the development needs of local industries and actively explores and practices the construction of professional groups based on local characteristic resources. Following the model of “integration of science and engineering, professional collaboration”, the university leverages the pioneering advantages of its Chemistry major. By integrating the distinct service-oriented features of the Metallurgical Engineering and Food Quality and Safety majors, it has established a professional group characterized by the “one core, two wings” approach: Chemistry as the core major (“one core”) and Metallurgical Engineering and Food Quality and Safety as the supporting majors (“two wings”). Taking advantage of its geographical location, Honghe University engages in international exchanges for talent cultivation and research cooperation with Vietnamese universities, thereby broadening students’ global perspectives and developing a unique pathway for talent cultivation. The majors within this professional group are all first-class construction majors in Yunnan Province and exemplary in ideological and political education within the university. The quality of talent cultivation has steadily improved, significantly enhancing the university’s ability to support regional economic and social development and drive innovation-led growth.

Key words: Application-oriented talents, Integration of science and engineering, Border region, Local characteristic resources, Talent cultivation pathways