Abstract: This article presents a 45-minute instructional design as a teaching-plan-example within the “101 Plan” organic chemistry curriculum, specifically focusing on named reactions in amine synthesis. The selected reactions, including Gabriel synthesis, Staudinger reaction, and Hofmann rearrangement, are systematically taught through the implementation of the BOPPPS teaching model. Through guided case studies of these representative reactions, students are expected to achieve deep mechanistic understanding and develop strategic thinking in synthetic design, thereby enhancing their ability to apply theoretical knowledge to practical scenarios and facilitating knowledge transfer and integration. Furthermore, this instructional approach cultivates a research-oriented mindset among students, characterized by a systematic problem-solving process: identifying problems, designing solutions, and implementing strategies. By integrating contemporary research findings into the curriculum, it also fosters a sustainable development perspective and stimulates innovative thinking in organic chemistry.

Key words: “101 Plan”, Amine synthesis, Named reaction, Knowledge point, BOPPPS model, Teaching plan