Matteson反应在有机合成中的应用：基础到前沿

doi:10.12461/PKU.DXHX202411023

Abstract

Abstract: The Matteson reaction has garnered significant attention in recent years as one of the cornerstone methodologies for organoboron compound synthesis, demonstrating remarkable utility in complex molecule construction and pharmaceutical development. This comprehensive review systematically examines the Matteson reaction, beginning with an elucidation of its fundamental principles and mechanistic underpinnings to establish a conceptual framework. Subsequently, we provide a critical analysis of contemporary advancements in its practical applications, particularly highlighting its pivotal role as a key transformation in the total synthesis of complex natural products and the production of pharmaceutically relevant intermediates.

Key words: Organoboron compounds, Synthetic intermediates, Matteson reaction, Carbon-added/Homologation reaction

Yansong Xiao, Yi Huang, Xingxing Ma, Qiuling Song. The Matteson Reaction in Organic Synthesis: From Fundamentals to Frontiers[J].University Chemistry, 2025, 40(10): 114-120.

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The Matteson Reaction in Organic Synthesis: From Fundamentals to Frontiers

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