Abstract:

In this project, we innovatively redesigned the experiment "Determination of Catalytic Activity of Oxidation Gold Nanoparticles in Benzyl Alcohol Oxidation reaction". ¹⁹F NMR, which is widely used in scientific research, is introduced into the teaching experiment as a kinetic detection method. The reaction substrate was replaced by fluorobenzyl alcohol, and the reaction rate constant and activation energy of substituents at different positions were compared through team cooperation. During the experiment, students can learn the principle and practical operation of NMR, compare the effect of substituent on catalytic reaction, and have a deeper understanding of catalytic mechanism combined with the theoretical knowledge of organic chemistry. The project realizes the organic combination of the dynamics teaching of ¹⁹F NMR detection with the theoretical knowledge of organic chemistry and instrumental analysis technology, and cultivates the students' ability of active thinking and solving practical problems.

Key words: ¹⁹F NMR, Catalytic oxidation, Gold nanoparticles, Fluorobenzyl alcohol, Substituent effect