University Chemistry ›› 2023, Vol. 38 ›› Issue (8): 95-100.doi: 10.3866/PKU.DXHX202208102

• Chemistry Laboratory • Previous Articles     Next Articles

Synthesis of Macrocyclic Semithiobambus[6]uril for Transmembrane Anion Transportation: A Comprehensive Chemical Experiment for Undergraduate Students

Yinan Lu, Yichen Luo, Yan Li, Hongcheng Sun(), Junqiu Liu   

  • Received:2022-08-19 Accepted:2022-09-19 Published:2022-10-10
  • Contact: Hongcheng Sun


Herein, a comprehensive experiment was carried out to study the macrocyclic molecules of semithiobambus[6]uril (stBU[6]), involving the preparation, characterization, and performance testing. Through a series of fluorescence tests, the students are guided to understand the mechanism of ion transmembrane transport, familiarize themselves with large-scale instruments, and broaden their horizons to lay a good foundation for improving their comprehensive practical skills.

Key words: Fluorescence detection, Transmembrane transport, Artificial ion channel