University Chemistry ›› 2023, Vol. 38 ›› Issue (11): 323-336.doi: 10.3866/PKU.DXHX202301032

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A Brief Discussion of Molecular Editing Technology: The Building Block Game on Atomic Scale

Yuxiang Zhou, Yanghaoyu Tan, Zirui Ye, Mingbang Wang, Jiang Bian()   

  • Received:2023-01-26 Accepted:2023-03-31 Published:2023-04-12
  • Contact: Jiang Bian E-mail:bj@pku.edu.cn

Abstract:

With the organic synthetic chemistry developed in recent years, molecular editing technology has gradually demonstrated significant advantages in both synthetic chemistry and retrosynthetic analysis and plays an important part in the decoration and the optimization of drugs. We introduce some of the reactions about molecular editing, such as skeletal rearrangement and C—H functionalization, and the prospect of molecular editing in the future is discussed in the final part.

Key words: Molecular editing, Organic synthesis, Methodology