肿瘤原位荧光标记技术设计和探索虚拟仿真实验

doi:10.3866/PKU.DXHX202303056

Abstract

Abstract:

In situ fluorescence imaging technology offers an efficacious method for garnering biochemical information at cellular and organismal scales. Prolonged in situ labeling techniques, using solid-state fluorescent probes, are particularly suited for precise imaging and surgical navigation during tumor resections. However, the inherent challenges, including extended research cycles, high costs, and substantial resource utilization, often preclude their inclusion in undergraduate teaching. To surmount these obstacles, we transformed the latest research findings into a "virtual simulation experiment of tumor in situ fluorescent labeling technology design and exploration" utilizing the U3D three-dimensional virtual reality technology platform. Through an interactive 37-step operation and exploratory teaching approach centred on crucial scientific issues, we aim to hone students' practical skills, foster scientific thinking and innovative awareness, actively guide the development of their scientific literacy, and instil values pertinent to scientific research.

Key words: In situ fluorescence imaging, Virtual simulation experiment, Fluorescent probes, Surgical navigation

Shuangyan Huan, Ke Li, Xiaobing Zhang, Weiping Luo, Yuzhi Wang, Xia Yin, Tianbing Ren, Hongxia Gao, Zhiwu Liang. Virtual Simulation Experiment for the Design and Exploration of Tumor in Situ Fluorescence Labeling Technology[J].University Chemistry, 2023, 38(11): 171-179.

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References 8

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Virtual Simulation Experiment for the Design and Exploration of Tumor in Situ Fluorescence Labeling Technology

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