Wittig反应的立体选择性

doi:10.12461/PKU.DXHX202410046

Abstract

Abstract: The Wittig reaction is a well-established method for synthesizing olefins. However, undergraduate organic chemistry textbooks often provide only a cursory overview of the mechanisms and stereoselectivities associated with these reactions. This article aims to enhance the existing literature by introducing several proposed mechanisms of the Wittig reaction and their corresponding explanations for stereoselectivity. It is our hope that this discussion will aid students in understanding the mechanisms and stereoselective outcomes of the Wittig reaction, thereby reinforcing their foundational knowledge of organic chemistry.

Key words: Wittig reaction, Phosphorus ylide, Reaction mechanism, Stereoselectivity

Zhi Chai, Huashan Huang, Xukai Shi, Yujing Lan, Zhentao Yuan, Hong Yan. The Stereoselectivity of the Wittig Reactions[J].University Chemistry, 2025, 40(8): 192-201.

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The Stereoselectivity of the Wittig Reactions

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