Abstract: This paper presents a comprehensive applied chemistry experiment focused on the preparation and application of a novel Chromium (VI) detection test paper. The experiment encompasses key concepts and techniques from both organic and analytical chemistry. A critical approach to enhancing college students’ scientific research literacy, innovative potential, and problem-solving capabilities in today’s context involves translating cutting-edge research findings into practical laboratory instruction. Utilizing tri(4-imidazolylphenyl) amine and benzyl bromide as starting materials, we synthesized ImBn-Br, an imidazolium compound capable of selectively recognizing Cr₂O₇²⁻. This compound was subsequently developed into a chromium detection test strip, facilitating rapid and visual detection of Cr₂O₇²⁻ in water samples. This experiment not only provides students with essential skills in heating reflux, filtration, and solution preparation but also fosters their interest in pollution detection and remediation while enhancing their environmental awareness. The methodology employed is innovative, visually accessible, and highly practical, making it well-suited for implementation in senior undergraduate courses.

Key words: Comprehensive applied chemistry experiment, Science and education transformation, Imidazolium, Chromium (VI) detection test paper