冠醚在人工离子转运系统中的应用

doi:10.12461/PKU.DXHX202501010

Abstract

Abstract: Crown ethers, a distinctive class of ether compounds characterized by their unique structural features, have garnered increasing recognition in the scientific community. Recent advancements have witnessed remarkable innovations in the application of crown ethers for constructing artificial transmembrane ion transport systems. The utilization of diverse crown ether structures and assembly motifs has significantly broadened the research landscape, encompassing the development of transmembrane artificial ion channels, seawater treatment, lithium extraction from salt lakes, and battery technologies. By integrating principles from supramolecular chemistry and biology, along with interdisciplinary approaches, these novel biomimetic artificial ion transporters, distinguished by their innovative structures and unique functionalities, are poised to make substantial contributions to the pharmaceutical and chemical industries.

Key words: Crown ether, Transmembrane transport, Selective separation, Alkali Metals

Jing Tan, Bo Zheng, Lingyan Gao. Application of Crown Ether-Based Artificial Ion Transporters[J].University Chemistry, 2026, 41(2): 232-237.

References

[1] (a) Pedersen, C. J. J. Am. Chem. Soc. 1967, 89 (10), 2495. (b) Pedersen, C. J. J. Am. Chem. Soc. 1967, 89 (26), 7017.
[2] (a) Cram, D. J.; Cram, J. M. Science 1974, 183 (4127), 803. (b) Lehn, J. M. Pure&Appl. Chem. 1978, 50, 871.
[3] The 1987 Nobel Prize in Chemistry. [2024-12-27]. https://www.nobelprize.org/prizes/chemistry/1987/press-release/
[4] Williams, G. T.; Haynes, C. J. E.; Fares, M.; Caltagirone, C.; Hiscock, J. R.; Gale, P. A. Chem. Soc. Rev. 2021, 50, 2737.
[5] Huang, T.; Alyami, M.; Kashab, N. M.; Nunes, S. P. J. Mater. Chem. A 2021, 9, 18102.
[6] 阮文娟, 李悦, 耿文超, 郭东升. 大学化学, 2023, 38 (12), 114.
[7] Gokel, G. W.; Leevy, W. M.; Weber, M. E. Chem. Rev. 2004, 104, 2723.
[8] 邢其毅, 裴伟伟, 徐瑞秋, 裴坚. 基础有机化学. 第4版. 北京: 北京大学出版社, 2017: 319–330.
[9] Djalali, S.; Marqués, P. S.; Frank, B. D.; Zeininger, L. Adv. Funct. Mater. 2022, 32 (2), 2107688.
[10] Ranno, L.; Tan, Y. Z.; Ong, C. S.; Guo, X.; Koo, K. N.; Li, X.; Wang, W.; Serna, S.; Liu, C.; Rusli; et al. Nat. Commun. 2024, 15, 3820.
[11] He, L.; Zhang, T.; Zhu, C.; Yan, T.; Liu, J. Chem. Eur. J. 2023, 29 (25), e202300044.
[12] Johnson, T. G.; Langton, M. J. J. Am. Chem. Soc. 2023, 145, 27167.
[13] Shen, J.; Ren, C.; Zeng, H. Acc. Chem. Res. 2022, 55, 1148.
[14] Ren, C.; Shen, J.; Zeng, H. J. Am. Chem. Soc. 2017, 139, 12338.
[15] Shen, J.; Ye, R.; Zeng, H. Angew. Chem. Int. Ed. 2021, 60, 12924.
[16] Huo, Y.; Zeng, H. Acc. Chem. Res. 2016, 49, 922.
[17] Zhang, H.; Ye, R.; Mu, Y.; Li, T.; Zeng, H. Nano Lett. 2021, 21, 1384.
[18] Ren, C.; Chen, F.; Ye, R.; Ong, Y. S.; Lu, H.; Lee, S. S.; Ying, J. Y.; Zeng, H. Angew. Chem. Int. Ed. 2019, 58, 8034.
[19] Shen, J.; Han, J. J. Y.; Ye, R.; Zeng, H. Sci China Chem. 2021, 64 (12), 2154.
[20] Ye, R.; Ren, C.; Shen, J.; Li, N.; Chen, F.; Roy, A.; Zeng, H. J. Am. Chem. Soc. 2019, 141, 9788.
[21] Chen, S.; Wang, Y.; Nie, T.; Bao, C.; Wang, C.; Xu, T.; Lin, Q.; Qu, D. H.; Gong, X.; Yang, Y; et al. J. Am. Chem. Soc. 2018, 140, 17992.
[22] Wang, C.; Yang, H.; Xiang, Y.; Pang, S.; Bao, C.; Zhu, L. Front. Chem. 2021, 9, 667472.
[23] Wang, C.; Wang, S.; Yang, H.; Xiang, Y.; Wang, X.; Bao, C.; Zhu, L.; Tian, H.; Qu, D. H. Angew. Chem. Int. Ed. 2021, 60, 14836.
[24] Ye, K.; Zhang, Z.; Yan, Z.; Pang, S.; Yang, H.; Sun, X.; Liu, C.; Zhu, L.; Lian, C.; Bao, C. Sci. China Chem. 2023, 66 (8), 2300.
[25] Li, N.; Shen, J.; Ang, G. K.; Ye, R.; Zeng, H. CCS Chem. 2020, 2, 2269.
[26] Li, N.; Chen, F.; Shen, J.; Zhang, H.; Wang, T.; Ye, R.; Li, T.; Loh, T. P.; Yang, Y. Y.; Zeng, H. J. Am. Chem. Soc. 2020, 142, 21082.
[27] Wang, W. Z.; Huang, L. B.; Zheng, S. P.; Moulin, E.; Gavat, O.; Barboiu, M.; Giuseppone, N. J. Am. Chem. Soc. 2021, 143, 15653.
[28] Li, C.; Wu, Y.; Zhu, Y.; Yan, J.; Liu, S.; Xu, J.; Fa, S.; Yan, T.; Zhu, D.; Yan, Y.; et al. Adv. Mater. 2024, 36, 2312352.
[29] Yang, H.; Yi, J.; Pang, S.; Ye, K.; Ye, Z.; Duan, Q.; Yan, Z.; Lian, C.; Yang, Y.; Zhu, L.; et al. Angew. Chem. Int. Ed. 2022, 61, e202204605.
[30] Ye, T.; Hou, G.; Li, W.; Wang, C.; Yi, K.; Liu, N.; Liu, J.; Huang, S.; Gao, J. Nat. Commun. 2021, 12, 5231.
[31] Ye, T.; Gao, H.; Li, Q.; Liu, N.; Liu, X.; Jiang, L.; Gao, J. Angew. Chem. Int. Ed. 2024, 63, e202316161.
[32] Jiang, C.; Bai, S.; Li, J.; Wang, M.; Zhou, Y.; Hou, Y. J. Membr. Sci. 2025, 714, 123372.
[33] Li, J.; Shi, Y.; Qi, C.; Zhang, B.; Xing, X.; Li, Y.; Chen, T.; Mao, X.; Zuo, Z.; Zhao, X.; et al. Angew. Chem. Int. Ed. 2023, 62, e202309918.
[34] Chen, Q.; Lin, M.; Li, X.; Du, Z.; Liu, Y.; Tang, Y.; Yan, Y.; Zhu, K. Angew. Chem. Int. Ed. 2024, e202407575.
[35] Li, M.; Wu, J.; You, Z.; Dai, Z.; Gu, Y.; Shi, L.; Wu, M.; Wen, Z. Angew. Chem. Int. Ed. 2024, 63, e202403521.
[36] Sauvage, J. P. Angew. Chem. Int. Ed. 2017, 56, 11080.
[37] Stoddart, J. F. Angew. Chem. Int. Ed. 2017, 56, 11094.
[38] Feringa, B. L. Angew. Chem. Int. Ed. 2017, 56, 11060.
[39] Balzani, V.; Credi, A.; Raymo, F. M.; Stoddart, J. F. Angew. Chem. Int. Ed. 2000, 39, 3348.
[40] Zheng, B.; Wang, F.; Donga, S.; Huang, F. Chem. Soc. Rev. 2012, 41, 1621.
[41] Cakmak, S. E.; Leigh, D. A.; McTernan, C. T.; Nussbaumer, A. L. Chem. Rev. 2015, 115, 10081.
[42] 成楚旸. 大学化学, 2017, 32 (1), 1.

Application of Crown Ether-Based Artificial Ion Transporters

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