更深度的“照相”技术——质谱成像的发展与应用

doi:10.3866/PKU.DXHX201907028

Abstract

Abstract:

Mass spectrometry imaging is a frontier research field derived from the development of mass spectrometry. It is the combination of mass spectrometry and imaging techniques, which can get the molecular structure information and the spatial distribution information at the same time without labeling. Mass spectrometry imaging has tremendous applications in the fields of biomedicine, clinical medicine, pathology and life science research for the analyzing of small molecules, peptides, metabolites, etc.

Key words: Mass spectrometry imaging, Application and development

Yingchen Yang,Qifa Chen,Yan Xia. More in-Depth "Photography" Technology: The Development and Application of Mass Spectrometry Imaging[J].University Chemistry, 2020, 35(3): 47-53.

Figures/Tables 4

References 53

1	Dihazi H. ; Bohrer R. ; Jahn O. ; Lenz C. ; Majcherczyk A. ; Schmidt B. ; Urlaub H. ; Valerius O. ; Asif A. R. Expert Rev. Proteomics 2013, 10 (1), 17.
2	Vachet R. W. Nat. Nanotechnol. 2015, 10, 103. doi: 10.1038/nnano.2015.4
3	Briggs D. Surf. Interface Anal. 1983, 5, 113. doi: 10.1002/sia.740050307
4	Lechene C. ; Hillion F. ; McMahon G. ; Benson D. ; Kleinfeld A. M. ; Kampf J. P. ; Distel D. ; Luyten Y. ; Bonventre J. ; Hentschel D. ; et al J. Biol 2006, 5, 20. doi: 10.1186/jbiol42
5	Winograd N. Anal. Chem. 2015, 87 (1), 328.
6	Winograd N. Anal. Chem. 2005, 77 (7), 142A.
7	Mahoney C. M. ; Roberson S. V. ; Gillen G. Anal. Chem. 2004, 76 (11), 3199. doi: 10.1021/ac035532n
8	Touboul D. ; Kollmer F. ; Niehuis E. J. Am. Soc. Mass Spectrom 2005, 16 (10), 1608. doi: 10.1016/j.jasms.2005.06.005
9	Li Z. ; Verkhoturov S. V. ; Schweikert E. A. Anal. Chem. 2006, 78 (21), 7410. doi: 10.1021/ac0603779
10	Rabbani S. ; Barber A. M. ; Fletcher J. S. ; Lockyer N. P. ; Vicerman J. C. Anal. Chem. 2011, 83 (10), 3793. doi: 10.1021/ac200288v
11	Ninomiya S. ; Nakata Y. ; Honda Y. ; Ichiki K. ; Seki T. ; Aoki T. ; Matsuo J. Appl. Surf. Sci. 2008, 255 (4), 1588. doi: 10.1016/j.apsusc.2008.05.004
12	Rabbani S. S. ; Barber A. ; Fletcher J. S. ; Lockyer N. P. ; Vickerman J. C. Anal. Chem. 2013, 85 (12), 5654. doi: 10.1021/ac4013732
13	Fletcher J. S. ; Rabbani S. ; Henderson A. ; Blenkinsopp P. ; Thompson S. P. ; Lockyer N. P. ; Vickerman J. C. Anal. Chem. 2008, 80 (23), 9058. doi: 10.1021/ac8015278
14	Carado A. ; Passarelli M. K. ; Kozole J. Anal. Chem. 2008, 80 (21), 7921. doi: 10.1021/ac801712s
15	Fisher G. L. ; Bruinen A. L. ; Potocnik N. O. ; Hammond J. S. ; Bryan S. R. ; Larson P. E. ; Heeren R. M. A. Anal. Chem. 2016, 88 (12), 6433. doi: 10.1021/acs.analchem.6b01022
16	Wucher A. ; Cheng J. ; Zheng L. ; Winograd N. Anal. Bioanal. Chem. 2009, 393, 1835. doi: 10.1007/s00216-008-2596-5
17	Goor O. J. G. M. ; Keizer H. M. ; Bruinen A. L. ; Schmitz M. G. J. ; Versteegen R. M. ; Janssen H. M. ; Heeren R. M. A. ; Janssen H. M. ; Heeren R. M. A. ; Danker P. Y. W. Adv. Mater. 2017, 29, 1604652. doi: 10.1002/adma.201604652
18	Dekas A. E. ; Poretsky R. S. ; Orphan V. J. Science 2009, 326 (5951), 422. doi: 10.1126/science.1178223
19	Lechene C. P. ; Luyten Y. ; McMahon G. ; Distel D. L. Science 2007, 317 (5844), 1563. doi: 10.1126/science.1145557
20	Mayali X. ; Weber P. K. FEMS Microbiology Ecology 2018, 94 (5), fiy047.
21	Rao A. N. ; Vandencasteele N. ; Gamble L. J. ; Grainger D. W. Anal. Chem. 2012, 84 (24), 10628. doi: 10.1021/ac3019334
22	Steinhauser M'. L. ; Bailey A. P. ; Senyo S. E. ; Guillermier C. ; Perlstein T. S. ; Gould A. P. ; Lee R. T. ; Lechene C. P. Nature 2012, 481 (7382), 516. doi: 10.1038/nature10734
23	Ostrowski S. G. ; Van Bell C. T. ; Winograd N. ; Ewing A. G. Science 2004, 305 (5680), 71. doi: 10.1126/science.1099791
24	Lozano M. M. ; Liu Z. ; Sunnick E. ; Janshoff A. ; Kumar K. ; Boxer S. G. J. Am. Chem. Soc. 2013, 135 (15), 5620. doi: 10.1021/ja310831m
25	Passarelli M. K. ; Newman C. F. ; Marshall P. S. ; West A. ; Gilmore I. S. ; Bunch J. ; Alexander M. R. ; Dollery G. T. Anal. Chem. 2013, 87 (13), 6696.
26	Caprioli R. M. ; Farmer T. B. ; Gile J. Anal. Chem. 1997, 69 (23), 4751. doi: 10.1021/ac970888i
27	Kompauer M. ; Heiles S. ; Spengler B. Nat. Method 2017, 14 (1), 90. doi: 10.1038/nmeth.4071
28	Qin L. ; Zhang Y. W. ; Liu Y. Q. ; He H. H. ; Han M. ; Li Y. Y. ; Zeng M. M. ; Wang X. D. Phytochem. Anal. 2018, 29 (4), 251.
29	Pratavieira M. ; Silva Menegasso A. R. ; Esteves F. G. ; Sato K. U. ; Malaspina O. ; Palma M. S. Phytochem. Anal. 2018, 17 (7), 2358.
30	Boersema P. J. ; Taouatas N. ; Altelaar A. F. M. ; Gouw J. W. ; Ross P. L. ; Pappin D. J. ; Heck A. J. R. ; Mohammed S. Mol. Cell Proteom. 2009, 8 (4), 650. doi: 10.1074/mcp.M800249-MCP200
31	Mekecha T. T. ; Amunugama R. ; Mcluckey S. A. J. Am. Soc. Mass Spectrom. 2006, 17 (7), 923. doi: 10.1016/j.jasms.2006.01.004
32	Alberts D. ; Pottier C. ; Smargiasso N. ; Baiwir D. ; Mazzucchelli G. ; Delvenne P. ; Kriegsmann M. ; Kazdal D. ; Warth A. ; Pauw E. D. ; Longuespee R. Proteom. Clin. Appl. 2018, 12 (1), 1700062. doi: 10.1002/prca.201700062
33	Yajima Y. ; Hiratsuka T. ; Kakimoto Y. ; Ogawa S. ; Shima K. ; Yamazaki Y. ; Yoshikawa K. ; Tamaki K. ; Tsuruyama T. Sci. Rep. 2018, 8, 7493. doi: 10.1038/s41598-018-25817-7
34	Spraggin J. M. ; Rizzo D. G. ; Moore J. L. ; Noto M. J. ; Skaar E. P. ; Caprioli R. M. Proteomics 2016, 16 (11-12), 1678. doi: 10.1002/pmic.201600003
35	Aichler M. ; Walch A. Lab. Investig. 2015, 95 (4), 422. doi: 10.1038/labinvest.2014.156
36	Smith A. ; Piga I. ; Galli M. ; Stella M. ; Denti V. ; Puppo M. D. ; Magni F. Int. J. Mol. Sci. 2017, 18 (12), 2588. doi: 10.3390/ijms18122588
37	Duenas M. E. ; Essner J. J. ; Lee Y. J. Sci. Rep. 2017, 7, 14949. doi: 10.1038/s41598-017-15020-5
38	Baker T. C. ; Han J. ; Borchers C. H. Curr. Opin. Biotechnol. 2017, 43, 62. doi: 10.1016/j.copbio.2016.09.003
39	Goodwin R. J. A. ; Nilsson A. ; Borg D. ; Langrudge-Smith P. R. R. ; Harrison D. J. ; Mackay C. L. ; Iverson S. L. ; Andren P. E. J. Proteom. 2012, 75 (16), 4912. doi: 10.1016/j.jprot.2012.07.006
40	Nilsson A. ; Goodwin R. J. A. ; Shariatgorji M. ; Vallianatou T. ; Webborn P. J. H. ; Andrem P. E. Anal. Chem. 2015, 87 (3), 1437. doi: 10.1021/ac504734s
41	Thomas A. ; Chaurand P. Bioanalysis 2014, 6 (7), 967. doi: 10.4155/bio.14.63
42	Wang J. ; Qiu S. ; Chen S. ; Xiong C. Q. ; Liu H. H. ; Wang J. Y. ; Zhang N. ; Hou J. ; He Q. ; Nie Z. X. Anal. Chem. 2015, 87 (1), 422.
43	Fulop A. ; Porada M. B. ; Marsching C. ; Blott H. ; Meyer B. ; Tambe S. ; Sandhoff R. ; Junker H. D. ; Hopf C. Anal. Chem. 2013, 85 (19), 9156. doi: 10.1021/ac4018154
44	Le C. H. ; Han J. ; Borchers C. H. Anal. Chem. 2012, 84 (19), 8391. doi: 10.1021/ac301901s
45	Francese S. ; Bradshaw R. ; Flinders B. ; Mitchell C. ; Belay S. ; Cicero L. ; Clench M. R. Anal. Chem. 2013, 85 (10), 5240. doi: 10.1021/ac4007396
46	Wang S. S. ; Wang Y. J. ; Zhang J. ; Sun T. Q. ; Guo Y. L. Anal. Chem. 2019, 91 (6), 4070. doi: 10.1021/acs.analchem.8b05680
47	Takats Z. ; Wiseman J. M. ; Gologan B. ; Cooks R. G. Science 2004, 306 (5695), 471. doi: 10.1126/science.1104404
48	Wiseman J. M. ; Ifa D. R. ; Song Q. Y. ; Cooks R. G. Angew. Chem. Int. Ed. 2006, 45 (43), 7188. doi: 10.1002/anie.200602449
49	Wiseman J. M. ; Ifa D. R. ; Zhu Y. ; Kissinger C. B. ; Manicke N. E. ; Kissinger P. T. ; Cooks R. G. PNAS 2008, 105 (47), 18120. doi: 10.1073/pnas.0801066105
50	Ellis S. R. ; Wu C. P. ; Deeley J. M. ; Zhu X. J. ; Truscott R. J. W. ; Panhuis M. ; Cooks R. G. ; Mitchell T. W. ; Blanksby S. J. J. Am. Soc. Mass Spectrom 2010, 21 (12), 2095. doi: 10.1016/j.jasms.2010.09.003
51	Jarmusch A. K. ; Alfaro C. M. ; Pirro V. ; Hattab E. M. ; Cohen-Gadol A. A. ; Cooks R. G. PLOS ONE 2016, 11 (9), e0160380.
52	Tata A. ; Perez C. J. ; Hamid T. S. ; Bayfield M. A. ; Ifa D. R. J. Am. Soc. Mass Spectrom. 2015, 26 (4), 641. doi: 10.1007/s13361-014-1039-0
53	Kumara P. M. ; Srimany A. ; Arunan S. ; Ravikanth R. U. S. ; Pradeep T. PLOS ONE 2016, 11 (6), e0158099. doi: 10.1371/journal.pone.0158099

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More in-Depth "Photography" Technology: The Development and Application of Mass Spectrometry Imaging

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