人名反应在有机化学课程教学中的作用：以Roskamp-Feng反应和Ullmann-Ma反应为例

doi:10.12461/PKU.DXHX202504079

Abstract

Abstract: Named reactions hold pivotal importance in organic chemistry education, with each reaction embodying the significant contributions of distinguished organic chemists and their research teams. Tracing the historical development of these named reactions and exploring the stories behind the scientists constitutes an essential component of ideological and political education in the curriculum. Among the multitude of chemical named reactions, those bearing Chinese scientists’ names remain exceptionally rare. This article examines the pedagogical value of named reactions in organic chemistry instruction, focusing on two representative examples: the Roskamp-Feng reaction and the Ullmann-Ma reaction. The discussion provides valuable insights for educators seeking to enhance the teaching of organic chemistry courses.

Key words: Organic chemistry, Named reaction, Roskamp-Feng reaction, Ullmann-Ma reaction, Teaching

Xuguang Liu, Caiwen Li, Honglei Ling, Mao Liang. The role of named reactions in organic chemistry teaching: case studies of the Roskamp-Feng and Ullmann-Ma reactions[J].University Chemistry, 2026, 41(7): 364-372.

References

[1] J.J. Li, Name Reactions: A Collection of Detailed Mechanisms and Synthetic Applications, 6th ed., Springer: Cham, Switzerland, 2021.
[2] L. Kürti, B. Czakó, Strategic Applications of Named Reactions in Organic Synthesis, Elsevier Inc: Amsterdam, the Netherlands, 2005.
[3] 黄培强. 有机人名反应、试剂与规则. 北京: 化学工业出版社, 2019.
[4] 韩广甸, 刘宏斌, 韩超, 马兆扬. 黄鸣龙还原反应——碳基和含官能团羰基的还原反应. 北京: 化学工业出版社, 2011.
[5] 陆涛, 胡春, 项光亚. 有机化学. 第9版. 北京: 人民卫生出版社, 2022.
[6] 沈海霞, 刘少卿, 沈如伟. 化学教育(中英文), 2024, 45(14), 1.
[7] 杨占会, 陈洋. 大学化学, 2021, 36(4), 2005028.
[8] 童敏, 樊敏, 钱丰清. 化学教育(中英文), 2023, 44(4), 6.
[9] 李厚金, 蓝文健. 大学化学, 2024, 39(4), 268.
[10] 马志强. 大学化学, 2025, 40(6), 326.
[11] 田添禾, 刘峰, 冯丽恒, 张变香. 大学化学, 2020, 35(12), 174.
[12] C.R. Christopher, E. J. Roskamp, J. Org. Chem. 1989, 54, 3258.
[13] W. Li, J. Wang, X.M. Feng, J. Am. Chem. Soc. 2010, 132, 8532.
[14] M.Y. Wang, W. Li, Chin. J. Chem. 2021, 39, 969.
[15] 张韶光, 张文雄. 大学化学, 2010, 25(6), 1.
[16] 王乃兴. 有机化学, 2011, 31(8), 1319.
[17] 戴立信. 化学进展, 2018, 30(9), 1257.
[18] Q. Cai, W. Zhou, Chin. J. Chem. 2020, 38, 879.
[19] D. Ma, Y. Zhang, J. Yao, S. Wu, F. Tao, J. Am. Chem. Soc. 1998, 120, 12459.
[20] W. Zhou, M. Fan, J. Yin, Y. Jiang, D. Ma, J. Am. Chem. Soc. 2015, 137, 11942.
[21] 刘磊, 陶兆林, 郑媛媛. 化工时刊, 2024, 38(2), 77.
[22] 刘振兴, 胡加恩, 程子石, 郝新奇. 大学化学, 2025, 40(6), 139.
[23] X.Q. Feng, H.F. Du, Chin. J. Chem. 2021, 39, 2016.
[24] 冯向青, 杜海峰. 大学化学, 2022, 37(1), 2112014.
[25] G. Strok, K. Zhao, Tetrahedron Lett. 1989, 30, 2173.
[26] Y. Wei, M. Shi, Org. Chem. Front. 2017, 4, 1876.
[27] D. Ma, Y. Lin, X. Lu, Y. Yu, Tetrahedron Lett. 1988, 29, 1045.
[28] 陈茂, 翁玥, 雷爱文. 化学进展, 2010, 22(7), 1341.
[29] X. Jiang, J. Zhang, S. Ma, J. Am. Chem. Soc. 2016, 138, 8344.
[30] J. Zhong, Q. Meng, B. Liu, X. Li, X. Gao, T. Lei, C. Wu, Z. Li, C. Tung, L. Wu, Org. Lett. 2014, 16, 1988.
[31] B. Yu, Acc. Chem. Res. 2018, 51, 507.
[32] Q. Xie, J. Hu, Chin. J. Chem. 2020, 38, 202.
[33] J.H. Xie, Q.L. Zhou, Acc. Chem. Res. 2008, 41, 581.
[34] Q. Xie, J. Hu, Acc. Chem. Res. 2024, 57, 693.

The role of named reactions in organic chemistry teaching: case studies of the Roskamp-Feng and Ullmann-Ma reactions

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