创新实验——AIE分子聚集态调控及其糖胺聚糖模式识别应用

doi:10.12461/PKU.DXHX202507084

Abstract

Abstract: Aggregation-induced emission (AIE) molecules have found extensive applications in biomedical research and related fields. This study develops a fluorescent sensor array by precisely controlling the aggregation states of 1-(4-carboxyphenyl)-1,2,2-triphenylethene on polyethyleneimine for pattern recognition of complex glycosaminoglycans. The experiment serves as an educational platform for students to explore cutting-edge interdisciplinary research spanning supramolecular chemistry, photochemistry, analytical chemistry, and pharmaceutical sciences. Participants will gain hands-on experience with fluorescence spectrophotometry and microplate reader operation, while mastering innovative approaches from fundamental AIE principles to practical detection applications.

Key words: Aggregation-induced emission, Polyethyleneimine, Pattern recognition, Glycosaminoglycan, Comprehensive experiment

Yubin Ding, Yanlin Fu, Ruiyue Hu, Huali Wan, Jiaxin Yu, Lei Wu. Innovation experiment: modulation of AIEgen aggregation states for pattern recognition of glycosaminoglycans[J].University Chemistry, 2026, 41(8): 331-338.

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Innovation experiment: modulation of AIEgen aggregation states for pattern recognition of glycosaminoglycans

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