大学化学 >> 2026, Vol. 41 >> Issue (8): 130-138.doi: 10.12461/PKU.DXHX202507079

教学研究与改革 上一篇    下一篇

研教融合型药学基础化学教学案例库的构建与思考

展鹏   

  1. 山东大学药学院药物化学研究所, 山东 济南 250012
  • 收稿日期:2025-07-20 录用日期:2025-08-27 发布日期:2026-08-25
  • 通讯作者: 展鹏 E-mail:13793130595@163.com Peng Zhan
  • 基金资助:
    山东省本科教学改革研究项目(M2023290);山东大学教育教学改革研究项目(2025Y155);2025年齐鲁医学特色本科教育教学研究(重点项目);齐鲁医学院研究生优质教育教学资源项目(qlyxyjs-2025Z11);2025年度山东大学课堂教学改革课程(序号186)

Construction and reflection on a research-education integrated teaching case database for pharmaceutical basic chemistry

Peng Zhan   

  1. Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, Shangdong Province, China
  • Received:2025-07-20 Accepted:2025-08-27 Published:2026-08-25
  • Contact: Peng Zhan E-mail:13793130595@163.com

摘要: 围绕“研教融合”理念,系统阐述了药学基础化学(无机化学)教学案例库的构建路径与实践经验。案例库以“前沿成果-基础原理-药学场景”三向贯通为核心,精选Nature、Science、Cell等顶级期刊成果,转化为可教学的典型案例,涵盖分子结构、配位化学、氧化还原、元素化学等知识点。案例设计突出“临床问题-药学前沿-中药专题-生命科学发现”四条主线,强化学生从分子层面理解药物机制与研发实践的能力。

关键词: 研教融合, 无机化学, 药学教育, 教学案例库

Abstract: This paper conducts a systematic elaboration on the development and implementation of a teaching case database for pharmaceutical basic chemistry (inorganic chemistry) within the framework of “research-education integration”. The database is characterized by a tripartite structure that connects “cutting-edge research findings-fundamental principles-pharmaceutical applications”. The case studies included in the database are carefully selected from top-tier journals such as Nature, Science, and Cell. These cases encompass key chemical concepts like molecular structures, coordination chemistry, redox reactions, and elemental chemistry. The design of the database emphasizes four thematic dimensions: clinical challenges, pharmaceutical innovations, traditional Chinese medicine applications, and life science discoveries, which enhances students' ability to understand drug mechanisms and development processes at the molecular level.

Key words: Research-education integration, Inorganic chemistry, Pharmaceutical education, Teaching case database