大学化学 >> 2025, Vol. 40 >> Issue (5): 66-75.doi: 10.12461/PKU.DXHX202503126

所属专题： 化学实验标准与规范建设

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有机化学实验重结晶基本操作规范建议

钱雪伟1,2, 孙兴文1, 李厚金3, 刘占祥4, 郑媛5, 吴琳6, 蔡双莲7, 熊英8, 余广鳌9, 刘庆文10, 韩杰11, 杜欣12, 袁呈山13, 张奇涵14, 张树永15, 张剑荣6   

  1. 1 复旦大学化学系, 化学国家级实验教学示范中心(复旦大学), 上海 200433;
    2 复旦大学高分子科学系, 聚合物分子工程国家重点实验室, 上海 200433;
    3 中山大学化学学院, 广州 510006;
    4 浙江大学化学系, 化学国家级实验教学示范中心(浙江大学), 杭州 310058;
    5 中国科学技术大学化学与材料科学学院, 化学国家级实验教学示范中心(中国科学技术大学), 合肥 230026;
    6 南京大学化学化工学院, 化学国家级实验教学示范中心(南京大学), 南京 210023;
    7 湖南大学化学化工学院, 长沙 410082;
    8 武汉大学化学与分子科学学院, 化学国家级实验教学示范中心(武汉大学), 武汉 430072;
    9 华中师范大学化学学院, 武汉 430079;
    10 吉林大学化学学院, 长春 130012;
    11 南开大学化学学院, 化学国家级实验教学示范中心(南开大学), 天津 300071;
    12 大连理工大学化学学院, 辽宁大连 116024;
    13 兰州大学化学化工学院, 兰州 730000;
    14 北京大学化学与分子工程学院, 化学国家级实验教学示范中心(北京大学), 北京 100871;
    15 山东大学化学与化工学院, 济南 250100
  • 收稿日期:2025-03-27 修回日期:2025-04-01 发布日期:2025-05-21
  • 通讯作者: 孙兴文 E-mail:sunxingwen@fudan.edu.cn
  • 基金资助:
    中山大学本科教学质量工程项目；“教育部化学实验教学改革研究虚拟教研室”项目

Basic Operations and Specification Suggestions for Organic Chemical Recrystallization Experiments

Xuewei Qian1,2, Xingwen Sun1, Houjin Li3, Zhanxiang Liu4, Yuan Zheng5, Lin Wu6, Shuanglian Cai7, Ying Xiong8, Guangao Yu9, Qingwen Liu10, Jie Han11, Xin Du12, Chengshan Yuan13, Qihan Zhang14, Shuyong Zhang15, Jianrong Zhang6   

  1. 1 National Demonstration Center for Experimental Chemistry (Fudan University), Department of Chemistry, Fudan University, Shanghai 200433, China;
    2 State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai 200433, China;
    3 School of Chemistry, Sun Yat-Sen University, Guangzhou 510006, China;
    4 National Demonstration Center for Experimental Chemistry (Zhejiang University), Department of Chemistry, Zhejiang University, Hangzhou 310058, China;
    5 National Demonstration Center for Experimental Chemistry Education (University of Science and Technology of China), School of Chemistry and Materials Science, University of Science and Technology of China, Hefei 230026, China;
    6 National Demonstration Center for Experimental Chemistry Education (Nanjing University), School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China;
    7 College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China;
    8 National Demonstration Center for Experimental Chemistry Education (Wuhan University), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China;
    9 College of Chemistry, Central China Normal University, Wuhan 430079, China;
    10 National Demonstration Center for Experimental Chemistry Education (Jilin University), College of Chemistry, Jilin University, Changchun 130012, China;
    11 National Demonstration Center for Experimental Chemistry Education (Nankai University), College of Chemistry, Nankai University, Tianjin 300071, China;
    12 School of Chemistry, Dalian University of Technology, Dalian 116024, Liaoning Province, China;
    13 College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China;
    14 National Demonstration Center for Experimental Chemistry Education (Peking University), College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China;
    15 School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China
  • Received:2025-03-27 Revised:2025-04-01 Published:2025-05-21
  • Contact: Xingwen Sun E-mail:sunxingwen@fudan.edu.cn

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摘要： 对有机化学实验中常用的重结晶基本操作进行了全面深入的剖析，涵盖重结晶原理、溶剂选择、基本操作步骤以及注意事项等方面。通过理论阐述以及实际案例中的情况分析，详细探讨了各因素对重结晶效果的影响，旨在为有机化学实验提供一套系统、科学且实用的重结晶操作标准指南，实现有机化合物的高效、高质量纯化。

关键词: 有机化学实验, 纯化, 重结晶, 操作规范

Abstract: This article conducts a comprehensive and in-depth introduction of the basic recrystallization operations commonly used in organic chemistry experiments, covering the principles of recrystallization, solvent selection, basic operation steps, and precautions. Through theoretical explanations and analysis of actual cases, the influence of various factors on the recrystallization effect is discussed in detail, aiming to provide a set of systematic, scientific and practical recrystallization operation standard guidelines for organic chemistry experiments, so as to achieve efficient and high-quality purification of organic compounds.

Key words: Organic chemistry experiment, Purification, Recrystallization, Operational standard