Abstract: Originating from moldy sweet clover and developed in a biochemical laboratory, warfarin was initially deployed as a potent rodenticide. However, its journey into the medical field was met with skepticism and opposition, largely due to its reputation as a poison and circulating rumors. Scientists eventually uncovered warfarin’s anticoagulant mechanism and demonstrated the benefits of its use in anticoagulation therapy for patients. Since then, warfarin and its derivatives have become key agents in both anticoagulant treatment and rodent control.

Key words: Anticoagulant, Dicoumarol, Vitamin K, Vitamin K epoxide reductase