University Chemistry ›› 2022, Vol. 37 ›› Issue (12): 2112058.doi: 10.3866/PKU.DXHX202112058

• Chemistry Laboratory • Previous Articles     Next Articles

Controllable Synthesis of Superparamagnetic Magnetic Iron Oxide Nanoparticles and Induction Heating Studies: A Comprehensive Chemistry Experiment

Tingbin Zhang1, Junjie Lu1, Ying Qiu1, Huan Zhang1, Xiaoli Liu2, Mingli Peng1, Haiming Fan1,*()   

  1. 1 College of Chemistry and Materials Science, Northwest University, Xi'an 710127, China
    2 The College of Life Sciences & School of Medicine, Northwest University, Xi'an 710069, China
  • Received:2021-12-22 Accepted:2022-03-10 Published:2022-03-30
  • Contact: Haiming Fan E-mail:fanhm@nwu.edu.cn

Abstract:

Superparamagnetic magnetic iron oxide nanoparticles (SPIONs) show unique magnetic properties and good biocompatibility and have been used extensively in the biomedical field. Of particular interest is the ability of SPIONs to produce thermal energy in response to an external alternating magnetic field, which has shown potential for the treatment of tumors. This study details the synthesis of monodispersed SPIONs and investigates their size-and magnetic field-dependent inductive heating properties. It will encourage students to learn about the controllable synthesis of SPIONs and to understand the mechanism behind magnetic heat induction. This comprehensive experiment considers a cutting-edge topic with great potential for disease treatment, serving to broaden students' horizons, inspire their interest in scientific research and cultivate their awareness of scientific innovation.

Key words: Superparamagnetic iron oxide nanoparticles, Magnetic hyperthermia, Specific absorption rate, Alternating magnetic field, Comprehensive chemistry experiment