基于镍纳米团簇-铕混合物的纸基比率荧光传感器检测四环素——推荐一个研究型综合化学实验

doi:10.3866/PKU.DXHX202301023

Abstract

Abstract:

This study presents a research-oriented comprehensive chemistry experiment project. Specifically, a fluorometric sensor based on a nickel nanocluster (NiNC)–europium complex (denoted as NiNCs-Eu³⁺) was developed for the detection of tetracyclines (TCs). This experiment includes the preparation and characterization of NiNCs-Eu³⁺, performance analysis of the response to TCs, construction of the paper-based sensor, and investigation of its visual identification. Overall, this "visible" integrated chemistry experiment is expected to promote the development of comprehensive experimental skills and research capabilities of students because it involves a strongly comprehensive process and simple operation and exhibits high feasibility.

Key words: Nickel nanoclusters (NiNCs), Tetracyclines (TCs), Paper-based fluorescent probe, Comprehensive chemical experiment

Yulin Wang, Jinting Chen, Weitian Han, Xiuzhen Qiu. Ratiometric Paper-based Fluorescent Sensor Based on Nickel Nanocluster-Europium Mixture for Detection of Tetracyclines: A Research-Oriented Comprehensive Chemistry Experiment[J].University Chemistry, 2023, 38(10): 243-249.

Figures/Tables 6

References 12

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种类	原始浓度/(µmol·L⁻¹)	添加浓度/(µmol·L⁻¹)	自来水			湖水
种类	原始浓度/(µmol·L⁻¹)	添加浓度/(µmol·L⁻¹)	检测浓度/(µmol·L⁻¹)	回收率/%	RSD/%	检测浓度/(µmol·L⁻¹)	回收率/%	RSD/%
TC	0	5.00	4.59	91.80	3.20	4.47	89.40	1.79
		10.00	9.02	90.20	3.22	8.91	89.10	2.34
		20.00	19.11	95.55	2.08	18.18	90.90	3.83
OTC	0	5.00	4.71	94.20	3.32	4.62	92.40	1.72
		10.00	9.25	92.50	4.06	9.25	92.50	3.68
		20.00	18.24	95.20	1.90	19.52	97.60	3.22

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Ratiometric Paper-based Fluorescent Sensor Based on Nickel Nanocluster-Europium Mixture for Detection of Tetracyclines: A Research-Oriented Comprehensive Chemistry Experiment

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