University Chemistry ›› 2023, Vol. 38 ›› Issue (4): 88-97.doi: 10.3866/PKU.DXHX202211050

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Mystery in the Palm of Your Hand: Chiral Identification Using Optical Rotation Measurements and Specificity for Chiral Pollution Detection

Qilin Liu1, Yi Wu1, Yi Luo1, Yuan Liu2,*(), Kaiqun Wu1,*()   

  1. 1 College of Chemistry, Sichuan University, Chengdu 610065, China
    2 Experiment Teaching Center of Basic Chemistry, Sichuan University, Chengdu 610207, China
  • Received:2022-11-15 Accepted:2023-01-11 Published:2023-03-23
  • Contact: Yuan Liu, Kaiqun Wu E-mail:yuan2006122108@sina.com;877279887@qq.com

Abstract:

Even though chiral compounds are ubiquitous, the general public is rarely aware of them. In this study, we perform three basic experiments using a kaleidoscope, simple optometer, and chiral indicator. Kaleidoscopes can be used to easily distinguish chiral compounds from non-chiral ones. Simple optometers can be used to directly distinguish levorotary from dextrorotary substances and determine the rotation degree of chiral substances. Chiral indicators can be used to distinguish enantiomers via color changes, which are visible to the naked eye. Because chiral indicators do not require instrumentation, they are suitable for identifying chiral substances in research settings. The experiments are thorough and easy to perform, and the observed phenomena are vivid and thought-provoking. Therefore, we believe that the experiments herein can be used by the general public to evaluate the physical and chemical properties of chiral compounds. Moreover, the experiments emphasize the practical applications of science concepts, demonstrating the attractiveness of chirality and chemistry.

Key words: Kaleidoscope, Simple optometer, Chiral identification, Teaching experiment, Multilevel science popularization