Abstract: Magnetic Particle Imaging (MPI), an emerging molecular imaging technology, has demonstrated remarkable potential in preclinical medical applications, particularly in stem cell tracking and immunotherapy. Distinguished by its unique imaging principles, high spatial sensitivity, absence of ionizing radiation, and excellent temporal resolution, MPI represents a significant advancement in biomedical imaging. This article presents a first-person perspective on MPI's developmental trajectory, fundamental technical principles, progress in preclinical applications, as well as current challenges and future prospects. Our objective is to provide readers with a comprehensive picture of this rising star's critical value and promising developmental in the medical field.

Key words: Magnetic Particle Imaging, Molecular Imaging, Preclinical Applications, Popularization of science