University Chemistry ›› 2026, Vol. 41 ›› Issue (9): 202-209.doi: 10.12461/PKU.DXHX202507027

• Science Education • Previous Articles     Next Articles

Self-description of hydrogen nuclei: fundamental principles and medical applications of magnetic resonance imaging

Bao Yu1, Xinyi Zhao1, Huan Zhang2, Yiwen Li3, Mingli Peng1, Yongchen Gou3, Guang Jia3, Haiming Fan1   

  1. 1 College of Chemistry and Materials Science, Northwest University, Xi'an 710127, Shaanxi Province, China;
    2 Medical Imaging Center, The West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China;
    3 School of Computer Science and Technology, Xidian University, Xi'an 710126, Shaanxi Province, China
  • Received:2025-07-03 Accepted:2025-09-15 Published:2026-09-01
  • Contact: Mingli Peng, Haiming Fan E-mail:mlpeng@nwu.edu.cn;fanhm@nwu.edu.cn

Abstract: Magnetic resonance imaging (MRI) has emerged as an indispensable diagnostic tool in modern medicine, particularly for malignant tumors, neurological disorders, and cardiovascular diseases. Its clinical advantages include the absence of ionizing radiation, unlimited penetration depth, superior soft tissue resolution, and multi-parametric, multi-sequence imaging capabilities. From clinical diagnosis to scientific research, MRI plays a pivotal role in early disease detection, treatment monitoring, and prognosis evaluation. Recent advancements in artificial intelligence and superconducting technologies have further driven innovations in rapid high-resolution imaging, AI-assisted diagnostic interpretation, ultra-low-field and ultra-high-field MRI systems, and portable devices, heralding even broader applications for this technology. Told from the unique perspective of a hydrogen nucleus, this article walks the reader through the fundamentals of MRI, demystifying how this technology is used in medical diagnostics.

Key words: Magnetic resonance imaging, Contrast agent, Biological chemistry, Science popularization