Abstract:

The direct oxidative C(sp³)-H functionalization reaction has long been considered as one of the most efficient and straightforward synthetic protocol for the construction of C-C bonds. Recently, the synthesis of substituted quinolines via C(sp³)-H functionalization of glycine derivatives has gained widespread attention from the chemists. Recent progresses on the C(sp³)-H functionalization of glycine derivatives and their applications in the synthesis of substituted quinolines are described in this paper. The aims are to broaden students' vision and stimulate their interest in scientific research through the introduction of innovative scientific research.

Key words: C(sp³)-H functionalization, Glycine derivatives, Quinolines