融入课程思政的“截短侧耳素类抗生素泰妙菌素的合成及表征”化学创新实验教学设计

doi:10.12461/PKU.DXHX202511036

Abstract

Abstract: This study focuses on the synthesis of tiamulin, a pleuromutilin-class antibiotic, using pleuromutilin as the starting material through a designed efficient and continuous convergent synthetic route. Implemented as an open innovation experiment for third-year undergraduates at our institution, this project not only enhances students' practical skills in organic synthesis but also cultivates their national identity and patriotism through integrated ideological and political education. Such comprehensive training establishes a solid foundation for their future contributions to China's scientific research endeavors.

Key words: Structural modification of natural products, Pleuromutilin antibiotics, Tiamulin, Innovative teaching experiment

Hui Shao, Huan Jiao, Qi Zhang, Yuming Zhao, Mingyu Yang. Teaching design of a chemical innovation experiment: synthesis and characterization of Pleuromutilin antibiotic Tiamulin with integrated curriculum-based ideological and political education[J].University Chemistry, 2025, (): 2511036.

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Teaching design of a chemical innovation experiment: synthesis and characterization of Pleuromutilin antibiotic Tiamulin with integrated curriculum-based ideological and political education

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