大学化学 >> 2026, Vol. 41 >> Issue (4): 289-296.doi: 10.12461/PKU.DXHX202507006

科普 上一篇    下一篇

一颗医学“新星”MPI的崛起之路

羊福美1, 白雨欣1, 张珍1, 罗佳1, 苟永宸2, 彭明丽1, 贾广2, 樊海明1   

  1. 1 西北大学化学与材料科学学院, 化学国家级实验教学示范中心, 陕西 西安 710127;
    2 西安电子科技大学计算机科学与技术学院, 陕西 西安 710126
  • 收稿日期:2025-07-03 录用日期:2025-08-27 发布日期:2026-04-24
  • 通讯作者: 彭明丽, 贾广 E-mail:mlpeng@nwu.edu.cn;gjia@xidian.edu.cn Mingli Peng, Guang Jia
  • 基金资助:
    国家重点研发计划项目(2022YFB3203800,2021YFA1201400)；国家自然科学基金(82227802,22072115,62471370)；陕西省科技计划重点研发项目(2024SF-YBXM-40)；西北大学本科人才建设项目(XM05232381)。

The Rising Path of MPI: A New Star in Medical Imaging Innovation

Fumei Yang1, Yuxin Bai1, Zhen Zhang1, Jia Luo1, Yongchen Gou2, Mingli Peng1, Guang Jia2, Haiming Fan1   

  1. 1 National Chemistry Experimental Teaching Demonstration Center, College of Chemistry and Materials science, Northwest University, Xi'an 710127, Shaanxi Province, China;
    2 School of Computer Science and Technology, Xidian University, Xi'an 710126, Shaanxi Province, China
  • Received:2025-07-03 Accepted:2025-08-27 Published:2026-04-24
  • Contact: Mingli Peng, Guang Jia E-mail:mlpeng@nwu.edu.cn;gjia@xidian.edu.cn

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摘要： 磁粒子成像(MPI)作为一项新兴的分子影像技术，凭借独特的成像原理，高空间灵敏度，无电离辐射安全性，以及高时间分辨成像等特点，在临床前医学应用尤其在干细胞追踪和免疫治疗上展现出巨大的发展潜力。本文以第一人称的视角，向读者介绍MPI的发展历程、技术原理、临床前应用进展以及面临的挑战与未来展望，旨在向读者全面呈现这一科技新起之秀在医学领域的重要价值和发展前景。

关键词: 磁粒子成像, 分子影像, 临床前应用, 科普

Abstract: Magnetic Particle Imaging (MPI), an emerging molecular imaging technology, has demonstrated remarkable potential in preclinical medical applications, particularly in stem cell tracking and immunotherapy. Distinguished by its unique imaging principles, high spatial sensitivity, absence of ionizing radiation, and excellent temporal resolution, MPI represents a significant advancement in biomedical imaging. This article presents a first-person perspective on MPI's developmental trajectory, fundamental technical principles, progress in preclinical applications, as well as current challenges and future prospects. Our objective is to provide readers with a comprehensive picture of this rising star's critical value and promising developmental in the medical field.

Key words: Magnetic Particle Imaging, Molecular Imaging, Preclinical Applications, Popularization of science