Abstract: Under the “Four New Initiatives” in higher education, chemistry courses for non-chemistry majors often face challenges, such as a disconnect between foundational knowledge and specialized skills, a gap between theory and practice, and insufficient innovation and application. To address these issues, the School of Chemistry at Jilin University has developed a new curriculum system centered on the diverse needs of non-chemistry majors. This system focuses on three dimensions—teaching management, instructional methods, and faculty development—and promotes integration in five areas: teaching content and methods, disciplinary and professional competencies, practical innovation, in-class and extracurricular activities, and a diversified evaluation system. Through this approach, the “Chemistry + Four New Initiatives” integrated curriculum strengthens the connection between general chemistry education and professional training. Practice has shown that this model offers a practical solution for chemistry teaching in non-chemistry majors. It transforms foundational chemistry courses from a general education supplement into a key hub supporting the “Four New Initiatives”, providing a replicable and scalable example for basic course reform across diverse academic fields.

Key words: Chemistry, Four new initiatives, Non-chemistry majors, Integrated, Curriculum system