University Chemistry ›› 2016, Vol. 31 ›› Issue (10): 98-104.doi: 10.3866/PKU.DXHX201602011

• Chemistry Education-International • Previous Articles     Next Articles

A Brief Introduction to Suzuki-Miyaura Coupling Reaction in Organic Lab Abroad

Tian LI,Kai-Guo MA,Zhen GAO,Wei-Hong LI*()   

  • Published:2016-11-02
  • Contact: Wei-Hong LI E-mail:litian@pku.edu.cn

Abstract:

Suzuki-Miyaura reaction is a coupling process of aryl boric acid (boron ester) and aryl halide that catalyzed by palladium (0).The reaction shows well tolerance for various functional groups and is wildly applied in syntheses of natural products and organic materials.Recently,colleges abroad tried to introduce this reaction into the undergraduate organic lab.This paper collected the literatures in Journal of Chemical Education about the Suzuki-Miyaura reaction since 2000 and gave an overview.

Key words: Suzuki-Miyaura coupling reaction, Experimental design