三氯蔗糖简介及其在有机化学授课中的探索

doi:10.3866/PKU.DXHX202110040

Abstract

Abstract:

Carbohydrates play a pivotal role in our biological system and daily life, and have been considered as an important teaching content for organic chemistry. Sucralose which is derived from sucrose is a new type of sweetener with great economic value and can be served as a good teaching material for undergraduate course. This article describes the properties, discovery, synthesis and application of sucralose and also discusses the possibility of sucralose becoming a subject in the organic chemistry course, which is a new exploration of integrating practical applications of fine organic products into organic chemistry teaching.

Key words: Sweetener, Sucralose, Carbohydrate, Chemical synthesis

Chunfa Xu, Ping Chen, Yaofeng Yuan. The Brief Introduction and Exploration of Sucralose in the Organic Chemistry Teaching[J].University Chemistry, 2022, 37(7): 2110040.

Figures/Tables 3

References 13

1	McMurry, J. Organic Chemistry, 8th ed.; Cengage Learning: Belmont, VA, USA, 2011; pp. 1033–1034.
2	Jones, M.; Fleing, S. A. Organic Chemistry, 4th ed.; W. W. Norton & Company: New York, NY, USA, 2010; pp. 1164–1164.
3	郑建仙低能量食品, 北京: 中国轻工业出版社, 2001, 1-429.
4	Hough, L. Chem. Soc. Rev 1985, 14, 357. doi: 10.1039/cs9851400357
5	Hough, L.; Phadnis, S. P.; Tarelli. E. Carbohydr. Res 1975, 44, 35.
6	Fairclough, P.; Hough, L.; Richardson, A. Carbohydr. Res 1975, 40, 285. doi: 10.1016/S0008-6215(00)82610-5
7	Mufti, K. S.; Khan, R. A. Process for the Preparation of 4, 1', 6'-trichloro-4, 1', 6'-trideoxygalactosucrose (TGS). USA. Pat. 4380476, 1983.
8	Khan, R. A.; Mufti, K. S.; Patel, G. D. Trichloro, 6-substituted Sucrose Compounds, Composition and Uses Therefor. USA. Pat. 4612373, 1986.
9	Simpson, P. J. Sucrose Alkyl 4, 6-orthoacylates. USA. Pat. 4889928, 1989.
10	黄文, 贝慧玲中国食品添加剂, 2003, (6),85.
11	骆希明牙膏工业, 2004, (4),39.
12	Resendez, A.; Halim, M. A.; Singh, J.; Webb, D.; Singaram, B. Org. Biomol. Chem 2017, 15, 9727. doi: 10.1039/C7OB01893B
13	祝洪艳, 张秋梅, 王国丽, 林海成, 何萍, 于海忠, 程鹏飞中国实验方剂学杂志, 2015, 21 (7),8.

[1]	Yuheng Zhou. Colorful Chemistry in University: Exploring the Beauty of Transition Elements [J]. University Chemistry, 2025, 40(6): 303-309.
[2]	Hong Yan, Wenfeng Wang, Keyin Ye, Yaofeng Yuan. Organic Electrochemistry and Its Integration into Chemistry Teaching [J]. University Chemistry, 2025, 40(5): 301-310.
[3]	Jiajie Li, Xiaocong Ma, Jufang Zheng, Qiang Wan, Xiaoshun Zhou, Yahao Wang. Recent Advances in In-Situ Raman Spectroscopy for Investigating Electrocatalytic Organic Reaction Mechanisms [J]. University Chemistry, 2025, 40(4): 261-276.
[4]	Caixia Lin, Ting Liu, Zhaojiang Shi, Hong Yan, Keyin Ye, Yaofeng Yuan. Innovative Experiment of Electrochemical Dearomative Spirocyclization of N-Acyl Sulfonamides [J]. University Chemistry, 2025, 40(4): 359-366.
[5]	Ke Liu, Mingjing Deng, Jingbo Chang, Ailing Wang, Guoshuai Wu, Longyang Dian. Electrochemistry Mediated Direct Amination to Construct the Hemiaminal Ether Skeletons (HESs) [J]. University Chemistry, 2025, 40(2): 272-277.
[6]	Shuhui Li, Yujing Zhou, Haitao Tang. Overview of Organic Electrochemical Synthesis [J]. University Chemistry, 2025, 40(2): 210-215.
[7]	Ping Song, Nan Zhang, Jie Wang, Rui Yan, Zhiqiang Wang, Yingxue Jin. Experimental Teaching Design on Synthesis and Antitumor Activity Study of Cu-Pyropheophorbide-a Methyl Ester [J]. University Chemistry, 2024, 39(6): 278-286.
[8]	Li Jiang, Changzheng Chen, Yang Su, Hao Song, Yanmao Dong, Yan Yuan, Li Li. Electrochemical Synthesis of Polyaniline and Its Anticorrosive Application: Improvement and Innovative Design of the "Chemical Synthesis of Polyaniline" Experiment [J]. University Chemistry, 2024, 39(3): 336-344.
[9]	Caixia Lin, Zhaojiang Shi, Yi Yu, Jianfeng Yan, Keyin Ye, Yaofeng Yuan. Ideological and Political Design for the Electrochemical Synthesis of Benzoxathiazine Dioxide Experiment [J]. University Chemistry, 2024, 39(2): 61-66.
[10]	Jingpei Jia, Youai Qiu. Experimental Design for the Electrochemical Nucleophilic Aromatic Substitution Reaction [J]. University Chemistry, 2024, 39(12): 265-272.
[11]	Balati Hasimujiang, Caifeng Hu, Yawen Huang, Mu Chen, Xinwei Hu, Zhixiong Ruan. Comprehensive Experimental Design for Solvent-Controlled Electrochemical Synthesis of Selenium-Containing Pyranone and Chalcone [J]. University Chemistry, 2024, 39(12): 273-283.
[12]	Tingting Yu, Si Chen, Lianglong Sun, Tongtong Shi, Kai Sun, Xin Wang. Comprehensive Experimental Design for the Photochemical Synthesis, Analysis, and Characterization of Difluoropyrroles [J]. University Chemistry, 2024, 39(11): 196-203.
[13]	Wenli Zhou, Bing Zhang, Wenli Song, Jilin Zhang, Zhongxian Qiu, Yue Han, Chengzhi Li, Liping Yu. Hydrophobic Modification of Inorganic Perovskite Quantum Dots and LED Applications: Recommending a Comprehensive Chemistry Experiment for Undergraduates [J]. University Chemistry, 2023, 38(8): 192-199.
[14]	Minling Jiang, Tian He, Shouchun Yin. Know the Sweetness and Enjoy the "Sweet" Life [J]. University Chemistry, 2022, 37(9): 2203082-.
[15]	Menglong Zhao, Dailei Yuan, Zi Ye, Fang Fang, Yuena Yu. Electrooxidative Cross-Coupling with Hydrogen Evolution to Construct C—N Bonds: Design and Exploration of Electrochemical Technology in Organic Chemistry Laboratory Teaching [J]. University Chemistry, 2022, 37(5): 2109108-.

The Brief Introduction and Exploration of Sucralose in the Organic Chemistry Teaching

RichHTML

PDF

Like

Knowledge

Abstract

Cite this article

share this article

Figures/Tables 3

References 13

Related Articles 15

Metrics

Recommended 0