苯乙烯的原子转移自由基聚合(ATRP)——一个典型的“活性”/可控自由基聚合实验

doi:10.3866/PKU.DXHX202209048

Abstract

Abstract:

Experimental teaching of polymer chemistry in science colleges mainly focuses on traditional polymerization methods, making it difficult to meet the rapid development of polymer science and the requirements of student training. We introduced atom transfer radical polymerization into the experimental course of polymer chemistry and designed a series of contents, including experimental operation, polymerization process monitoring, and instrumental characterization, which are conducive for students to understand polymer research and master the basic skills of the field. We combined cutting-edge scientific research and experimental teaching to cultivate comprehensive scientific research literacy in students, providing new ideas for training students in science colleges.

Key words: Polymer chemistry, Undergraduate experimental teaching, Atom transfer radical polymerization

Xianzhe He, Ying Yu, Lei Tao. Atom Transfer Radical Polymerization (ATRP) of Styrene: A Typical "Living"/Controlled Radical Polymerization Experiment[J].University Chemistry, 2023, 38(8): 225-231.

Figures/Tables 6

References 14

1	Staudinger H. Ber. Dtsch. Chem. Ges. 1920, 53, 1073. doi: 10.1002/cber.19200530627
2	张希. 高分子学报, 2020, 51 (1), 1.
3	姚明; 姜志国. 化工高等教育, 2021, 38 (4), 110.
4	秦建彬; 史学涛; 张广成; 狄西岩; 顾军渭; 闫毅. 大学化学, 2022, 37 (3), 2105050.
5	于莹; 陶磊; 许华平. 大学化学, 2015, 30 (3), 9.
6	Wang J. S. ; Matyjaszewski K. J. Am. Chem. Soc. 1995, 117, 5614. doi: 10.1021/ja00125a035
7	Kato M. ; Kamigaito M. ; Sawamoto M. ; Higashimura T. Macromolecules 1995, 28, 1721. doi: 10.1021/ma00109a056
8	Truong N. P. ; Jones G. R. ; Bradford K. G. E. ; Konkolewicz D. ; Anastasaki A. Nat. Rev. Chem. 2021, 5, 859.
9	Beers K. L. ; Matyjaszewski K. ; Woodworth B. J. Chem. Educ. 2001, 78, 544.
10	Tsarevsky N. V. ; Woodruff S. R. ; Wisian-Neilson P. J. J. Chem. Educ. 2016, 93, 1452.
11	颜静; 耿旺昌; 姚东东; 闫毅. 化学教育, 2020, 41 (14), 32.
12	田元; 郑莹光; 王国斌; 裘祖文; 沈家骢. 高等学校化学学报, 1987, 8 (9), 851.
13	卢江; 梁晖. 高分子化学, 第2版北京: 化学工业出版社, 2009, 179- 182.
14	潘祖仁. 高分子化学, 第5版北京: 化学工业出版社, 2011, 100- 102.

试剂名称	纯度	生产厂家
苯乙烯	98%	阿拉丁试剂
溴化亚铜	98%	国药试剂
五甲基二乙烯三胺	98%	ACROS
2-溴丁酸乙酯	98%	百灵威试剂
苯甲醚	99%	Alfa Aesar
甲醇	99%	General
N, N-二甲基甲酰胺(DMF)	98%	ACROS
丙酮	99%	通广试剂
醋酸	99%	国药试剂
碱性氧化铝(100–200目)	98%	国药试剂
中性氧化铝(100–200目)	98%	国药试剂

试剂名称	型号	生产厂家
电子天平	ML-204	梅特勒-托利多仪器有限公司(美国)
磁力搅拌器	RCT basic	艾卡仪器设备有限公司(德国)
凝胶渗透色谱仪	1260 Infinity	安捷伦科技有限公司(美国)
循环水真空泵	SHB-111	上海振捷实验设备有限公司(中国)
真空干燥箱	DZF-6020	上海一恒科学仪器有限公司(中国)

组别	1 h数均分子量/Da	1 h分子量分布	2.5 h数均分子量/Da	2.5 h分子量分布	产物质量/g	产率
1	2900	1.07	7300	1.21	0.61	13.5%
2	2300	1.05	4700	1.25	0.22	4.9%
3	2200	1.05	4600	1.12	0.31	6.9%
4	2700	1.07	6400	1.16	0.38	8.4%
5	2500	1.06	4400	1.09	0.06	1.3%
6	2700	1.06	4500	1.10	0.11	2.4%
7	2400	1.06	2800	1.16	未沉淀	/
8	2200	1.05	3000	1.21	未沉淀	/
9	2400	1.06	2800	1.16	未沉淀	/
10	2000	1.04	2900	1.07	未沉淀	/

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Atom Transfer Radical Polymerization (ATRP) of Styrene: A Typical "Living"/Controlled Radical Polymerization Experiment

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