Abstract: Electrochemical organic synthesis represents a crucial frontier in organic chemistry research, offering mild conditions and environmental friendliness. However, it has yet to be widely adopted in undergraduate laboratory teaching. This experiment is designed based on recent research findings to facilitate the nucleophilic aromatic substitution reaction of benzoic acid and 4-fluoroanisole under electrochemical conditions. The experiment includes four main components: product preparation, purification via column chromatography, structural characterization, and cyclic voltammetry (CV) analysis. The objective is to enhance students’ comprehensive experimental skills, introduce them to advanced organic chemistry topics, and instill an understanding of green chemistry principles.

Key words: Electrochemical synthesis, Radical chemistry, Nucleophilic aromatic substitution