基于科教协同育人的有机化学实验设计——以2-羟甲基-4,6-二叔丁基苯酚的亲核取代反应为例

doi:10.12461/PKU.DXHX202407031

Abstract

Abstract: The experimental phenomena observed in gas-liquid-solid reactions serve to stimulate students’ interest in learning. The intricate connections between gas generation, drying, and tail gas treatment equipment encourage students to adopt a mindset of understanding the sequence and significance of processes. Through the separation, purification, and characterization of products, students develop comprehensive skills in organic synthesis. Standardizing the use of concentrated sulfuric acid and managing hazardous gas treatments enhance students’ awareness of emergency protocols and environmental responsibility. Finally, by extending the experimental focus to a series of related reactions, students are guided to transition from theoretical knowledge to practical application.

Key words: Integration of science and education, Organic chemistry, Halogenated hydrocarbon, Nucleophilic substitution

Aiyi Xin, Jiawei Li, Xinyang Ran, Chuanjiang Fu, Zhiguo Wang. Collaborative Science and Education Based Experimental Design in Organic Chemistry: A Case Study of the Nucleophilic Substitution Reaction of 2-Hydroxymethyl-4,6-Di-Tert-Butylphenol[J].University Chemistry, 2025, 40(5): 366-375.

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Collaborative Science and Education Based Experimental Design in Organic Chemistry: A Case Study of the Nucleophilic Substitution Reaction of 2-Hydroxymethyl-4,6-Di-Tert-Butylphenol

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