Abstract: The textbook “Physical Chemistry Tutorial” from the “101 Plan” reshapes the content of physical chemistry courses from the atomic and molecular level, showcasing several distinctive key features: consistently applies a thermodynamic perspective grounded in atomic and molecular principles; systematically constructs the thermodynamics of intermolecular interactions; establishes a new understanding of solution structures and offers fresh insights into activity coefficients; incorporates extensive analysis of scientific history to distill scientific wisdom. Based on students’ feedback after the first round of teaching practice, this textbook helps students grasp the micro-level understanding and application of thermodynamics, playing a positive role in cultivating top-notch innovative talent in the field of chemistry.

Key words: Physical chemistry, “101 Plan” textbook, Thermodynamics