氧中心自由基

doi:10.12461/PKU.DXHX202405213

Abstract

Abstract: Free radicals are fundamental in organic chemistry, forming the cornerstone of organic reactions alongside other high-energy intermediates such as carbocations, carbanions, and carbenes. Among these, oxygen-centered radicals represent a particularly unique and important class of active intermediates. Their distinctive properties not only enable them to initiate a variety of organic reactions but also drive extensive research in healthcare and environmental protection. This article aims to thoroughly analyze and highlight the physicochemical properties and diverse synthesis strategies of four key oxygen-centered radicals: triplet oxygen (·O₂·), hydroxyl radical (HO·), superoxide anion radical (O₂^-·), and alkoxy radical (RO·). Additionally, it elucidates their specific application examples and significant impacts in the field of organic synthesis.

Key words: Free radical, Oxygen-centered radical, Reactive intermediate, Green chemistry

Yuxiao Hu, Bingbing Huang, Wenju Chang, Jie Shen. Oxygen-Centered Radicals[J].University Chemistry, 2025, 40(2): 216-227.

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Oxygen-Centered Radicals

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