University Chemistry ›› 2026, Vol. 41 ›› Issue (8): 350-362.doi: 10.12461/PKU.DXHX202507032

• Chemistry Laboratory • Previous Articles     Next Articles

Virtual simulation experiment for the synthesis and properties of near-infrared organic nanoparticles

Xinyu Xu1, Changjin Ou1, Chunxia Kong1, Weiliang Tian2, Huaming Wang3, Haijiao Wang3, Tao Tao1,2,3   

  1. 1 School of Chemistry and Materials Science, Nanjing University of Information Science & Technology, Nanjing 210044, Jiangsu Province, China;
    2 College of Chemistry and Chemical Engineering, Tarim University, Alear 843300, Xinjiang Uygur Autonomous Region, China;
    3 Department of Energy and Chemical Engineering, Xinxing Vocational and Technical College, Xinxing 839000, Xinjiang Uygur Autonomous Region, China
  • Received:2025-07-03 Accepted:2025-08-19 Published:2026-08-25
  • Contact: Tao Tao E-mail:taotao@nuist.edu.cn

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Abstract: Near-infrared (NIR) organic nanoparticles, as representative nanobiomaterials, have attracted extensive research attention in tumor phototherapy owing to their precise targeting capability, well-defined therapeutic efficacy, and superior imaging resolution. However, this interdisciplinary research involves high-risk procedures, substantial costs, and considerable experimental complexity, rendering its direct implementation in undergraduate education impractical. Utilizing U3D virtual reality technology, we have converted this research into a virtual simulation experiment featuring a 20-step interactive procedure combined with guided inquiry-based learning centered on key scientific questions. This pedagogical approach stimulates students' critical thinking, fosters scientific research competencies, enhances their ability to solve complex engineering problems, and demonstrates excellent visual teaching outcomes.

Key words: Organic nanoparticles, Tumor phototherapy, Charge-transfer complexes, Virtual simulation experiment