University Chemistry ›› 2018, Vol. 33 ›› Issue (8): 43-46.doi: 10.3866/PKU.DXHX201802007

• Chemistry Laboratory • Previous Articles     Next Articles

Synthesis of Acetylsalicylic Acid Catalyzed by HZSM-5: Recommendation of a Semi-Microscale Organic Chemistry Experiment

Liqi LI,Youxiang HE,Yuan ZHANG*()   

  • Received:2018-02-04 Published:2018-08-30
  • Contact: Yuan ZHANG


A semi-microscale organic chemistry experiment for the efficient synthesis of acetylsalicylic acid is designed, and the synthesis starts from salicylic acid and acetic anhydride with HZSM-5 as the catalyst at room temperature or heating conditions. Compared with the classical experimental method, the new experiment possesses the advantages of easy operation, high product yield and low pollution, which is more in line with the educational concepts of green chemistry.

Key words: Acetylsalicylic acid, HZSM-5 zeolite, Green chemistry