共价有机框架整体材料的制备及食品安全非靶向筛查应用——推荐一个仪器分析综合化学实验

doi:10.12461/PKU.DXHX202406013

Abstract

Abstract: This study recommends a practical, application-oriented comprehensive experiment in instrumental analysis for undergraduate students. Centered on non-targeted food safety screening, a covalent organic framework (COF)-based monolithic material (MF@COF composite) with melamine foam (MF) as the supporter was prepared and applied to sample pretreatment process of non-targeted analysis for food. The COF is in-situ grown and bonded onto the surface of the inexpensive and readily available MF, enabling effective purification of food matrices and complete recovery of chemical hazards while preventing secondary contamination. The experiment encompasses the synthesis and characterization of MF@COF, adsorption of phytochrome, recovery of chemical hazards, as well as post-experimental data processing and model analysis. Grounded in fundamental concepts such as Schiff base reaction, adsorption isotherm, and kinetics, the experiment strengthens students’ proficiency in UV-visible spectrophotometry, introduces the scientific research frontier of COF materials, and integrates real-world applications in food safety analysis. Combining fundamental knowledge with comprehensive and engaging experimental design, the experiment fosters students’ innovative thinking and practical skills while enhancing their interest and confidence in analytical chemistry.

Key words: Covalent organic framework, Food safety, Adsorption, Comprehensive chemistry experiment

Wei Li, Jinfan Xu, Yongjun Zhang, Ying Guan. Preparation of Covalent Organic Framework Monolithic Material for Non-Targeted Food Safety Screening: A Recommended Comprehensive Instrumental Analysis Chemistry Experiment[J].University Chemistry, 2025, 40(6): 276-285.

References

[1] 王京, 李琰, 南晶, 李一峻, 邱晓航, 丁飞. 大学化学, 2024, 39(1), 7.
[2] 李薇, 王晓涵, 陈燕, 唐安娜, 孔德明. 化学教育(中英文), 2023, 44(10), 1.
[3] Freund, R.; Zaremba, O.; Arnauts, G.; Ameloot, R.; Skorupskii, G.; Dinca, M.; Bavykina, A.; Gascon, J.; Ejsmont, A.; Goscianska, J.; et al. Angew. Chem. Int. Ed. 2021, 60, 23975.
[4] 许锦帆, 陈俊豪, 李薇, 孔德明. 分析测试学报, 2023, 42(10), 1381.
[5] Chen, T.; Yu, K. F.; Dong, C. X.; Yuan, X.; Gong, X.; Lian, J.; Cao, X.; Li, M. Z.; Zhou, L.; Hu, B. W.; et al. Coord. Chem. Rev. 2022, 467, 214615.
[6] Nguyen, H. L.; Hanikel, N.; Lyle, S. J.; Zhu, Z. H.; Proserpio, D. M.; Yaghi, O. M. J. Am. Chem. Soc. 2020, 142(5), 2218.
[7] Li, W.; Jin, W. L.; Jiang, H. X.; Wang, R.; Jia, H.; Liu, J. Q.; Tang, A. N.; Zhu, L. N.; Kong, D. M. Chem. Eng. J. 2023, 455, 140900.
[8] Li, W.; Wang, X. H.; Liu, J. Q.; Jiang, H. X.; Cao, D. X.; Tang, A. N.; Kong, D. M. Talanta 2023, 265, 124880.
[9] 李积慧, 韩健, 陈建新. 大学化学, 2023, 38 (8), 275.
[10] 农业农村部. NY/T 3082–2017水果、蔬菜及其制品中叶绿素含量的测定分光光度法. 北京: 中华人民共和国农业部, 2017: 1–2.
[11] 国家标准化管理委员会. GB/T 21517–2008饲料添加剂叶黄素. 北京: 中国标准出版社, 2008: 1–6.
[12] 黄光, 李磊, 张丁逸, 王幸泽, 黄余改, 梁文慧, 郭志芬, 矫文美. 大学化学, 2024, 39 (8), 174.
[13] 乔正平, 尹明大, 许先芳, 黄华珍, 闫素君, 彭慧娟, 毛宗万. 大学化学, 2018, 33 (9), 75.
[14] 马莎莎, 杨祖金, 张建勇. 大学化学, 2024, 39 (8), 314.
[15] 国家标准化管理委员会. GB 23200.121–2021食品安全国家标准植物源性食品中331种农药及其代谢物残留量的测定液相色谱-质谱联用法. 北京: 中国标准出版社, 2021: 1–70.
[16] Li, W.; Jiang, H. X.; Cui, M. F.; Wang, R.; Tang, A. N.; Kong, D. M. J. Hazard. Mater. 2022, 432, 128705.

Preparation of Covalent Organic Framework Monolithic Material for Non-Targeted Food Safety Screening: A Recommended Comprehensive Instrumental Analysis Chemistry Experiment

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