University Chemistry ›› 2023, Vol. 38 ›› Issue (5): 188-192.doi: 10.3866/PKU.DXHX202207021

• Chemistry Laboratory • Previous Articles     Next Articles

A Comprehensive Design Experiment of Instrumental Analysis: Comparison of Two Electrochemical Sensors for Determining Glucose

Chuanen Guo2, Jingzheng Wang1, Xiaolei Wang1,*()   

  1. 1 College of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University, Jinan 250014, China
    2 Judicial Expertise Center, Shandong University of Political Science and Law, Jinan 250014, China
  • Received:2022-07-04 Accepted:2022-08-25 Published:2022-09-19
  • Contact: Xiaolei Wang


Comprehensive design experiment is an important way to cultivate the abilities of college students to independently solve problems and be innovative. A comprehensive design experiment titled "Comparison of two electrochemical sensor methods for determining glucose" was conducted. Students were asked to independently design two types of electrochemical sensors (i.e., a chemically modified electrode and biosensor) for determining glucose by conducting literature investigations. Comparing the linear ranges, sensitivities, and selectivities of the two sensor methods allowed students to independently choose the appropriate method for determining the glucose content in fruit juice. This project helped students to understand the advanced work involved in instrument-based analysis, improved their interest in learning and effective experimental teaching, and cultivated their scientific research skills through innovative learning.

Key words: Glucose, Instrumental analysis, Comprehensive design experiment, Biosensor, Chemically modified electrode