Abstract: Physical Chemistry is a mandatory course for pharmacy majors, playing a crucial role in guiding both theoretical understanding and practical applications in drug research, production, quality control, and storage. As a first-class offline course in Guangdong Province, this curriculum implements a student-centered approach, based on the “one core, three integrations, and three enhancements” teaching philosophy. The course integrates deeply with ideological and political education, professional knowledge, and cutting-edge scientific research, aiming to stimulate students’ interest, enhance their problem-solving abilities, and foster innovative scientific thinking. Additionally, the course incorporates rich ideological elements, helping students to cultivate correct worldviews and values. Through this comprehensive curriculum, students’ knowledge, skills, and overall competence are significantly improved, preparing them to become innovative talents with both expertise and integrity.

Key words: Physical chemistry, Student-centered, Ideological and political education, Innovative talent