Abstract: The difficulty in integrating various knowledge points and connecting them with medical applications has long been a persistent challenge in organic chemistry education for medical students. To address this issue, we implemented three strategic approaches to construct customized knowledge networks for achieving knowledge integration. First, we tailored basic concepts, challenging topics, and medical application cases to establish foundations, elucidate core principles, and provide practical relevance for current learning materials. Second, we employed functional group interconversions, the “structure-property-application” framework, reaction mechanisms, and comparative analysis of related concepts to establish connections between knowledge points. Finally, we incorporated specific medical application cases throughout the entire chapter-based learning process. Teaching practice results demonstrate that this approach significantly helps students clarify knowledge structures, systematically master key concepts, and ultimately achieve the goal of practical knowledge application.

Key words: Knowledge network, Knowledge integration, Organic chemistry, Construction strategies