Abstract: Following the Ministry of Education’s establishment of interdisciplinary disciplines as a distinct academic category, higher education institutions have placed increasing emphasis on cultivating interdisciplinary innovators. Drawing upon extensive interdisciplinary research experience and pedagogical reform insights, our team uses chemical biology education as a starting point to explore innovative approaches for cultivating interdisciplinary, versatile talents. As an emerging discipline integrating chemistry, biology, medical science, and pharmacology, chemical biology represents a paradigm of modern interdisciplinary science. The Comprehensive Chemical Biology Laboratory course serves as a crucial practical component for developing interdisciplinary thinking competencies. The primary pedagogical challenge lies in designing experimental curricula that enable students to synthesize multidisciplinary knowledge effectively. Our team addresses this challenge by translating selenium-related research achievements into instructional content, establishing multi-module experimental systems aligned with cutting-edge chemical biology research. This approach promotes practical application of cross-disciplinary knowledge and proposes an effective pedagogical framework for interdisciplinary talent development.

Key words: Chemical biology, Comprehensive Experiment, Frontier interdisciplinary discipline, Transformation of selenium-containing products